日本猫抓病中汉塞巴尔通体的血清学研究。

Serological study of Bartonella henselae in cat scratch disease in Japan.

作者信息

Yoshida H, Kusaba N, Omachi K, Miyazaki N, Yamawaki M, Tsuji Y, Nakahara K, Sumino M, Noudomi M, Shimokawa Y, Tanikawa K

机构信息

Department of Medicine, Yame General Hospital, Fukuoka, Japan.

出版信息

Microbiol Immunol. 1996;40(9):671-3. doi: 10.1111/j.1348-0421.1996.tb01126.x.

DOI:10.1111/j.1348-0421.1996.tb01126.x

PMID:8908613

Abstract

It has become clear that Bartonella henselae is a common cause of cat scratch disease (CSD). The indirect fluorescence antibody (IFA) test for detection of IgG and IgM antibodies to B. henselae concerning CSD showed that 5 (50%) of 10 patients with CSD had a serum IgG antibody titer of 1:128 or more and that 2 (20%) patients had a serum IgM antibody titer of 1:20 or more. One of 7 asymptomatic members of patients' families (14%) had IgG antibody to B. henselae at a titer of 1:256. IgM antibody to B. henselae was not detected in sera from the patients' families. Both IgG and IgM antibodies to B. henselae were not detected in sera from the healthy control group. These data suggest that B. henselae may be a cause of CSD in Japan.

摘要

现已明确，亨氏巴尔通体是猫抓病（CSD）的常见病因。针对CSD检测抗亨氏巴尔通体IgG和IgM抗体的间接荧光抗体（IFA）试验表明，10例CSD患者中有5例（50%）血清IgG抗体滴度为1:128或更高，2例（20%）患者血清IgM抗体滴度为1:20或更高。患者家庭的7名无症状成员中有1名（14%）抗亨氏巴尔通体IgG抗体滴度为1:256。在患者家庭成员的血清中未检测到抗亨氏巴尔通体IgM抗体。在健康对照组的血清中未检测到抗亨氏巴尔通体的IgG和IgM抗体。这些数据表明，在日本，亨氏巴尔通体可能是CSD的病因之一。