Simonic T, Sartyorelli P, Locatelli A
Ann Parasitol Hum Comp. 1975 Jul-Aug;50(4):461-8. doi: 10.1051/parasite/1975504461.
The authors have studied the bahaviour of cyclic 3',5'-AMP phosphodiesterase in the 2,000 g supernatant of the Fascilola hepatica homogenate, under basal conditions and after addition of various substances. Dopamine remarkably inhibits the enzyme activity, imidazole causes a strong activation, while serotonin, theophylline, PGE1 and PGF2alpha appear to be ineffective.
作者研究了肝片吸虫匀浆2000g上清液中环状3',5'-AMP磷酸二酯酶在基础条件下以及添加各种物质后的行为。多巴胺显著抑制该酶活性，咪唑引起强烈激活，而血清素、茶碱、前列腺素E1和前列腺素F2α似乎无作用。
