Stamatellos I, Koutsougeras G, Karamanidis D, Stamatopoulos P, Timpanidis I, Bontis J
First Academic Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, Greece.
Clin Exp Obstet Gynecol. 2007;34(1):35-8.
The purpose of this study was to evaluate the efficacy, safety and benefits of hysteroscopic surgery in the management of dysfunctional uterine bleeding or intrauterine lesions causing menstrual disorders in premenopausal women.
We enrolled in this study 228 patients who underwent operative hysteroscopy because of metrorrhagia due to endometrial polyps or submucous myomas diagnosed by hysterosalpingography, transvaginal ultrasound and diagnostic hysteroscopy. In addition, the study population included 27 patients who presented dysfunctional uterine bleeding resistant to medical therapy. These patients underwent total or partial transcervical resection of endometrium (TCRE).
Operative hysteroscopy was a successful procedure in 250 of the 255 cases (98%) but it needed to be repeated in three cases with large submucous myomas of type I and II and after two polypectomies. Mean duration of the procedure was 26.1 min (range 4-58) and mean postoperative hospital stay was six hours (range 2-48 hours). There were two cases with fluid overload and five with postoperative uterine bleeding reported in this study. During postoperative follow-up (12-36 months) the majority of patients (246/255 or 96.5%) were free of symptoms. After total or partial TCRE, 23/27 patients (85.2%) reported eumenorrhea or hypomenorrhea, 2/27 (7.4%) amenorrhea and 2/27 (7.4%) metrorrhagia (due to adenomyosis).
Hysteroscopic surgery is an effective and safe method for the management of benign intracavitary pathology or the treatment of dysfunctional uterine bleeding. In addition, it has the advantages of quick recovery, early return to normal activities and reduced hospital stay for the patient. Careful monitoring of the patients avoids serious complications.
本研究旨在评估宫腔镜手术治疗围绝经期妇女功能失调性子宫出血或引起月经紊乱的宫内病变的疗效、安全性及益处。
我们纳入了228例因子宫输卵管造影、经阴道超声及诊断性宫腔镜检查诊断为子宫内膜息肉或黏膜下肌瘤导致月经过多而接受宫腔镜手术的患者。此外,研究人群还包括27例药物治疗无效的功能失调性子宫出血患者。这些患者接受了子宫内膜全切除或部分切除(TCRE)。
255例患者中有250例(98%)宫腔镜手术成功,但3例I型和II型大黏膜下肌瘤患者及2例息肉切除术后患者需要再次手术。手术平均时长为26.1分钟(范围4 - 58分钟),术后平均住院时间为6小时(范围2 - 48小时)。本研究报告了2例液体超负荷及5例术后子宫出血病例。术后随访(12 - 36个月)期间,大多数患者(246/255或96.5%)无症状。全切除或部分切除TCRE后,27例患者中有23例(85.2%)报告月经过多或月经量减少,2例(7.4%)闭经,2例(7.4%)月经过多(由子宫腺肌病引起)。
宫腔镜手术是治疗良性腔内病变或功能失调性子宫出血的一种有效且安全的方法。此外,它具有恢复快、能早期恢复正常活动及缩短患者住院时间的优点。对患者进行仔细监测可避免严重并发症。