Ho K M, Lee K Y, Williams T, Finn J, Knuiman M, Webb S A R
Department of Intensive Care, Royal Perth Hospital, Perth, WA 6000, Australia.
Anaesthesia. 2007 May;62(5):466-73. doi: 10.1111/j.1365-2044.2007.04999.x.
This study compared the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) II score with two organ failure scores in predicting hospital mortality of critically ill patients. A total of 1311 consecutive adult patients in a tertiary 22-bed multidisciplinary intensive care unit (ICU) in Western Australia were considered. The APACHE II score had a better calibration and discrimination than the Max Sequential Organ Failure Score (Max SOFA) (area under receiver operating characteristic (ROC) curve 0.858 vs 0.829), Admission SOFA (area under ROC 0.858 vs 0.791), and the first day or cumulative 5-day Royal Perth Hospital Intensive Care Unit (RPHICU) organ failure score (area under ROC 0.858 vs 0.822 and 0.819, respectively) in predicting hospital mortality. The APACHE II score predicted hospital mortality of critically ill patients better than the SOFA and RPHICU organ failure scores in our ICU.
本研究比较了急性生理学与慢性健康状况评估（APACHE）II评分与两种器官衰竭评分在预测重症患者医院死亡率方面的表现。研究纳入了西澳大利亚一家拥有22张床位的三级多学科重症监护病房（ICU）的1311例连续成年患者。在预测医院死亡率方面，APACHE II评分比最大序贯器官衰竭评分（Max SOFA）（受试者操作特征曲线下面积[ROC]为0.858对0.829）、入院时SOFA评分（ROC曲线下面积为0.858对0.791）以及皇家珀斯医院重症监护病房（RPHICU）第一天或累计5天的器官衰竭评分（ROC曲线下面积分别为0.858对0.822和0.819）具有更好的校准和辨别能力。在我们的ICU中，APACHE II评分在预测重症患者医院死亡率方面比SOFA评分和RPHICU器官衰竭评分表现更好。
