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通过荧光光谱法测定，利用解吸电喷雾电离质谱法（DESI-MS）检测阿托摩尔量的分析物。

Detection of attomole amounts of analyte by desorption electrospray ionization mass spectrometry (DESI-MS) determined using fluorescence spectroscopy.

作者信息

Bereman Michael S, Muddiman David C

机构信息

W.M. Keck FT-ICR Mass Spectrometry Laboratory, Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, USA.

出版信息

J Am Soc Mass Spectrom. 2007 Jun;18(6):1093-6. doi: 10.1016/j.jasms.2007.03.006. Epub 2007 Mar 21.

DOI:10.1016/j.jasms.2007.03.006
PMID:17448675
Abstract

We report the use of fluorescence spectroscopy to investigate the amount of material removed from a PTFE surface and detected during desorption electrospray ionization (DESI) mass spectrometry measurements. The fluorescence intensity before and after DESI analysis of rhodamine 6G is used to determine the amount of material removed from the surface per mass spectrum. Calculations indicate low attomole amounts are removed per linear ion trap mass spectrum.

摘要

我们报告了使用荧光光谱法来研究从聚四氟乙烯（PTFE）表面去除并在解吸电喷雾电离（DESI）质谱测量过程中检测到的物质的量。罗丹明6G的DESI分析前后的荧光强度用于确定每个质谱从表面去除的物质的量。计算表明，每个线性离子阱质谱去除的量为低阿托摩尔量级。

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Rapid Commun Mass Spectrom. 2007;21(7):1150-4. doi: 10.1002/rcm.2947.
2
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Rapid Commun Mass Spectrom. 2006;20(22):3409-11. doi: 10.1002/rcm.2759.
3
解吸电喷雾电离的构建：喷雾解吸收集对解吸和离子化的独立优化。
J Am Soc Mass Spectrom. 2012 Nov;23(11):1896-902. doi: 10.1007/s13361-012-0468-x. Epub 2012 Aug 21.
4
Enhanced ion signals in desorption electrospray ionization using surfactant spray solutions.使用表面活性剂喷雾溶液增强解吸电喷雾电离中的离子信号。
J Am Soc Mass Spectrom. 2010 Aug;21(8):1423-31. doi: 10.1016/j.jasms.2010.04.001. Epub 2010 Apr 8.
5
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6
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