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颈动脉体副神经节瘤:一名15岁青少年男孩身上的罕见肿瘤。

Carotid body paraganglioma: rare tumor in a 15-year-old adolescent boy.

作者信息

Zaupa Paola, Höllwarth Michael E

机构信息

Department of Pediatric Surgery, Medical University of Graz, Graz 8036, Austria.

出版信息

J Pediatr Surg. 2007 Apr;42(4):E13-7. doi: 10.1016/j.jpedsurg.2007.01.059.

Abstract

We report a 15-year-old adolescent boy with right-side carotid body paraganglioma (CBP). The diagnosis of CBP was suspected accidentally because of an asymptomatic mass in the right side of the neck and was confirmed by ultrasound, magnetic resonance imaging, and carotid arteriography. The CBP was successfully removed surgically by complete subadventitial excision without complications or neurologic sequelae. In addition, the patient had type 1 diabetes. Recently, it has been demonstrated that carotid body plays a role in the glucoregulation in vivo and that hypoglycaemic episodes in patients with diabetes may be related to alterations of carotid body sensory function. Paragangliomas are extremely rare in pediatric age, and it is not clear in our patient if diabetes also has a role in the development of CBP. We describe the case and analyse the treatment options of CBP.

摘要

我们报告一例15岁患有右侧颈动脉体副神经节瘤(CBP)的青少年男性。因右侧颈部无症状肿块,CBP诊断为偶然发现,后经超声、磁共振成像及颈动脉造影确诊。通过完整的外膜下切除手术成功切除CBP,无并发症或神经后遗症。此外,该患者患有1型糖尿病。最近有研究表明,颈动脉体在体内糖调节中发挥作用,糖尿病患者的低血糖发作可能与颈动脉体感觉功能改变有关。副神经节瘤在儿童期极为罕见,我们的患者中糖尿病是否也在CBP的发生中起作用尚不清楚。我们描述该病例并分析CBP的治疗选择。

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