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[颈动脉体瘤:10例报告]

[Carotid body tumors: report of ten cases].

作者信息

Soto G Sebastián, Valdés E Francisco, Krämer Sch Albrecht, Mariné M Leopoldo, Bergoeing R Michel, Mertens M Renato, Solar G Antonieta, Walton D Annerleim, Vergara G Jeannette

机构信息

Enfermedades Cardiovasculares, Hospital Clínico, Pontificia Universidad Católica de Chile, Santiago, Chile.

出版信息

Rev Med Chil. 2007 Nov;135(11):1414-20. Epub 2008 Jan 16.

PMID:18259652
Abstract

BACKGROUND

Carotid body tumors arise from a cellular conglomerate located at the carotid bifurcation. Progressive enlargement can involve the arterial wall and neighbor cranial nerves.

AIM

To report a series of 10 patients treated of carotid body tumors and review national experience.

PATIENTS AND METHODS

Between 1984 and 2006, we operated 8 women and 2 men, aged 19 to 75 years, with this type of tumor.

RESULTS

The most common cause for consultation was a cervical mass in 90%, with a mean evolution lapse of 13.2 months (range 3 to 126). In all cases, diagnosis was confirmed with angiographic imaging and histopathology. Ten tumors were surgically removed with no complications. Eighty percent of tumors were in stage II according to Shamblin classification. During long term follow up all patients have remained asymptomatic. Only 31 carotid body tumors have been reported in Chilean medical literature during a 43 year period.

CONCLUSIONS

Paragangliomas of the carotid body can be diagnosed in clinical grounds, requiring vascular imaging. These infrequent lesions are generally benign, early surgical removal by surgeons with vascular expertise avoids neurological and or vascular complications.

摘要

背景

颈动脉体瘤起源于位于颈动脉分叉处的细胞团块。肿瘤逐渐增大可累及动脉壁及相邻的颅神经。

目的

报告10例颈动脉体瘤患者的治疗情况并回顾国内经验。

患者与方法

1984年至2006年间,我们为8名女性和2名男性患者进行了手术,患者年龄在19至75岁之间,均患有此类肿瘤。

结果

90%的患者因颈部肿块前来就诊,肿块平均发展时间为13.2个月(3至126个月)。所有病例均通过血管造影成像和组织病理学确诊。10例肿瘤均通过手术切除,无并发症发生。根据沙姆林分类法,80%的肿瘤处于II期。在长期随访中,所有患者均无症状。在43年的时间里,智利医学文献中仅报道了31例颈动脉体瘤。

结论

颈动脉体副神经节瘤可根据临床表现诊断,需进行血管成像检查。这些罕见病变通常为良性,由具备血管专业知识的外科医生早期手术切除可避免神经和/或血管并发症。

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[Carotid body tumors: report of ten cases].[颈动脉体瘤:10例报告]
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