Keczkes K, Barker D J
Arch Dermatol. 1976 Jan;112(1):78-82.
A 60-year-old woman with a three-year history of an acquired hepatic cutaneous porphyria was discovered to have a porphyrin-producing malignant hepatoma. An attempt was made to treat her with fluorouracil perfused through a hepatic artery catheter. It did not produce shrinkage of the tumor, but the patient remains alive and ambulant a year after the infusion, although her skin lesions (scarring, bulla formation, and hyperpigmentation) on the fingers, back of hands, and face persist and she continues to excrete abnormally high quantities of porphyrin in her feces.
一名患有后天性肝皮肤卟啉症三年的60岁女性被发现患有产生卟啉的恶性肝癌。曾尝试通过肝动脉导管灌注氟尿嘧啶对她进行治疗。这并未使肿瘤缩小,但在输注一年后患者仍存活且可走动,尽管她手指、手背和面部的皮肤病变(瘢痕形成、水疱形成和色素沉着)依然存在,并且她粪便中卟啉的排泄量仍异常高。