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恶性肝癌合并获得性肝皮肤卟啉症。

Malignant hepatoma associated with acquired hepatic cutaneous porphyria.

作者信息

Keczkes K, Barker D J

出版信息

Arch Dermatol. 1976 Jan;112(1):78-82.

PMID:174497
Abstract

A 60-year-old woman with a three-year history of an acquired hepatic cutaneous porphyria was discovered to have a porphyrin-producing malignant hepatoma. An attempt was made to treat her with fluorouracil perfused through a hepatic artery catheter. It did not produce shrinkage of the tumor, but the patient remains alive and ambulant a year after the infusion, although her skin lesions (scarring, bulla formation, and hyperpigmentation) on the fingers, back of hands, and face persist and she continues to excrete abnormally high quantities of porphyrin in her feces.

摘要

一名患有后天性肝皮肤卟啉症三年的60岁女性被发现患有产生卟啉的恶性肝癌。曾尝试通过肝动脉导管灌注氟尿嘧啶对她进行治疗。这并未使肿瘤缩小,但在输注一年后患者仍存活且可走动,尽管她手指、手背和面部的皮肤病变(瘢痕形成、水疱形成和色素沉着)依然存在,并且她粪便中卟啉的排泄量仍异常高。

相似文献

1
Malignant hepatoma associated with acquired hepatic cutaneous porphyria.恶性肝癌合并获得性肝皮肤卟啉症。
Arch Dermatol. 1976 Jan;112(1):78-82.
2
Cutaneous porphyria due to a malignant primary hepatoma.原发性恶性肝癌所致的皮肤卟啉症。
Gastroenterology. 1970 Nov;59(5):779-83.
3
[Late cutaneous porphyria secondary to a primary cancer of the liver].[继发于原发性肝癌的迟发性皮肤卟啉症]
Ann Dermatol Venereol. 1988;115(10):1051-4.
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[Three cases of hepatocellular carcinoma, over 3 cm in diameter, with liver cirrhosis treated with combination of radiofrequency ablation and continuous hepatic arterial infusion chemotherapy].[三例直径超过3厘米的肝细胞癌合并肝硬化患者采用射频消融联合肝动脉持续灌注化疗治疗]
Gan To Kagaku Ryoho. 2007 Jul;34(7):1123-6.
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Letter: Leser-Trélat sign with porphyria cutanea tarda and malignant hepatoma.信件:伴迟发性皮肤卟啉症和恶性肝癌的Leser-Trélat征
Arch Dermatol. 1976 May;112(5):730.
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Symptomatic porphyria secondary to hepatocellular carcinoma.
Br J Dermatol. 1997 Jan;136(1):129-31.
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Occurrence of hepatocellular carcinoma in a case of hereditary coproporphyria.遗传性粪卟啉病患者发生肝细胞癌
Am J Gastroenterol. 1997 Aug;92(8):1389-90.
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A classification of liver tumours occurring in chronic hepatic porphyria.慢性肝卟啉症中发生的肝肿瘤分类。
Acta Univ Carol Med (Praha). 1987;33(3-4):237-44.
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Paraneoplastic Cutaneous Manifestations of Hepatocellular Carcinoma. A Systematic Review and Meta-analysis.肝细胞癌的副肿瘤性皮肤表现。一项系统评价和Meta分析。
J Cancer. 2024 Jan 1;15(4):1021-1029. doi: 10.7150/jca.88931. eCollection 2024.