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肝硬化患者行髋关节置换术的围手术期风险

Perioperative risk of hip arthroplasty in patients with cirrhotic liver disease.

作者信息

Moon Young-Wan, Kim Yong-Sik, Kwon Soon-Yong, Kim Shin-Yoon, Lim Seung-Jae, Park Youn-Soo

机构信息

Department of Orthopedic Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, 50 Ilwon-dong, Gangnam-gu, Seoul, Korea.

出版信息

J Korean Med Sci. 2007 Apr;22(2):223-6. doi: 10.3346/jkms.2007.22.2.223.

DOI:10.3346/jkms.2007.22.2.223
PMID:17449928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2693586/
Abstract

We retrospectively reviewed the complete medical records of 30 patients with a diagnosis of liver cirrhosis who had undergone hip arthroplasty at three academic institutions between October 1994 and May 2001. There were 26 males and 4 females with a mean age of 60 yr at index operation. Surgical procedures included 17 primary total hip arthroplasties (THA), 8 bipolar hemiarthroplasties, and 5 revision THAs. According to the Child-Pugh scoring system, 19 cirrhotic patients were categorized as class A, 9 as class B, and 2 as class C. Eight (26.7%) of the 30 patients had one or more perioperative complications. Of these, wound infection was the most common, with a rate of 10% (3 of 30 hips). Other perioperative complications included surgical site bleeding, coagulopathy, encephalopathy, gastrointestinal bleeding, pneumonia, and arrhythmia. Death occurred in 2 (6.7%) of the 30 patients; both were Child-Pugh's C cirrhotics. A higher Child-Pugh score (p=0.0001) and a high level of creatinine (p=0.0499) were associated with significantly increased perioperative complications or death. Our findings suggest that surgeons should be vigilant about perioperative complications in patients with advanced cirrhotic liver disease who undergo hip arthroplasty, albeit the mortality rates are relatively low in less severe cirrhotics.

摘要

我们回顾性分析了1994年10月至2001年5月期间在三家学术机构接受髋关节置换术的30例肝硬化患者的完整病历。其中男性26例,女性4例,初次手术时平均年龄为60岁。手术方式包括17例初次全髋关节置换术(THA)、8例双极半髋关节置换术和5例THA翻修术。根据Child-Pugh评分系统,19例肝硬化患者被归类为A类,9例为B类,2例为C类。30例患者中有8例(26.7%)发生了一种或多种围手术期并发症。其中,伤口感染最为常见,发生率为10%(30个髋关节中的3个)。其他围手术期并发症包括手术部位出血、凝血障碍、脑病、胃肠道出血、肺炎和心律失常。30例患者中有2例(6.7%)死亡;均为Child-Pugh C级肝硬化患者。较高的Child-Pugh评分(p=0.0001)和高水平的肌酐(p=0.0499)与围手术期并发症或死亡的显著增加相关。我们的研究结果表明,对于接受髋关节置换术的晚期肝硬化患者,外科医生应警惕围手术期并发症,尽管病情较轻的肝硬化患者死亡率相对较低。

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Operative risk of total hip and knee arthroplasty in cirrhotic patients.肝硬化患者全髋关节和膝关节置换术的手术风险
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