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肝硬化患者行髋关节或膝关节置换术的疗效分析

Outcome analysis of hip or knee arthroplasty in patients with cirrhotic liver disease.

作者信息

Seol Young-Jun, Yoon Taek-Rim, Lee Dong-Hyun, Lee Sun-Ho, Park Kyung-Soon

机构信息

Department of Orthopedic Surgery, Center for Joint Disease, Chonnam National University, Hwasun Hospital, Jeonnam, South Korea.

出版信息

J Orthop. 2017 Jan 4;14(1):171-175. doi: 10.1016/j.jor.2016.12.011. eCollection 2017 Mar.

DOI:10.1016/j.jor.2016.12.011
PMID:28070149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5219598/
Abstract

OBJECTIVE

Present helpful measures to prevent expected complications that occur in patients with liver cirrhosis undergoing arthroplasty.

METHODS

218 patients who underwent hip or knee arthroplasty were included in this study. Prognoses of patients with underlying disease of liver cirrhosis and those without are compared with measures.

RESULTS

Patients with liver cirrhosis show an increase in amount of bleeding, hospital stay and infection rate compared to those who do not.

CONCLUSION

The risk of arthroplasty on patients with liver cirrhosis is higher than normal patients. Surgeons should carefully assess all cirrhotic patients pre- and postoperatively.

摘要

目的

提出有助于预防肝硬化患者行关节置换术时出现预期并发症的措施。

方法

本研究纳入218例行髋关节或膝关节置换术的患者。比较了患有肝硬化基础疾病的患者和未患肝硬化基础疾病的患者的预后情况及相关措施。

结果

与未患肝硬化的患者相比，肝硬化患者的出血量、住院时间和感染率均有所增加。

结论

肝硬化患者行关节置换术的风险高于正常患者。外科医生应在术前和术后仔细评估所有肝硬化患者。

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本文引用的文献

1
Cirrhosis patients have increased risk of complications after hip or knee arthroplasty.肝硬化患者髋关节或膝关节置换术后并发症风险增加。
Acta Orthop. 2015 Feb;86(1):108-13. doi: 10.3109/17453674.2014.961397. Epub 2014 Sep 19.
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Increased complication rates after hip and knee arthroplasty in patients with cirrhosis of the liver.肝硬化患者行髋关节和膝关节置换术后并发症发生率增加。
Clin Orthop Relat Res. 2014 Sep;472(9):2774-8. doi: 10.1007/s11999-014-3681-z. Epub 2014 Jul 4.
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In-hospital surgical site infections after primary hip and knee arthroplasty--incidence and risk factors.初次髋关节和膝关节置换术后住院期间的手术部位感染-发生率和危险因素。
J Arthroplasty. 2013 Mar;28(3):385-9. doi: 10.1016/j.arth.2012.06.027. Epub 2012 Nov 8.
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Type and cause of liver disease in Korea: single-center experience, 2005-2010.韩国的肝病类型和病因：2005-2010 年单中心经验。
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Patient-related risk factors for postoperative mortality and periprosthetic joint infection in medicare patients undergoing TKA.医疗保险患者接受 TKA 后，与患者相关的术后死亡率和假体周围关节感染的风险因素。
Clin Orthop Relat Res. 2012 Jan;470(1):130-7. doi: 10.1007/s11999-011-2043-3.
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Morbidly obese, diabetic, younger, and unilateral joint arthroplasty patients have elevated total joint arthroplasty infection rates.病态肥胖、糖尿病、年轻和单侧关节置换患者的全关节置换感染率较高。
J Arthroplasty. 2009 Sep;24(6 Suppl):84-8. doi: 10.1016/j.arth.2009.05.016. Epub 2009 Jul 15.
7
The epidemiology of total knee replacement in South Korea: national registry data.韩国全膝关节置换术的流行病学：国家登记数据。
Rheumatology (Oxford). 2008 Jan;47(1):88-91. doi: 10.1093/rheumatology/kem308.
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Soluble CD163 from activated macrophages predicts mortality in acute liver failure.活化巨噬细胞产生的可溶性CD163可预测急性肝衰竭的死亡率。
J Hepatol. 2007 Nov;47(5):671-6. doi: 10.1016/j.jhep.2007.05.014. Epub 2007 Jun 21.
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J Korean Med Sci. 2007 Apr;22(2):223-6. doi: 10.3346/jkms.2007.22.2.223.
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