Salminen Paulina, Sala Eeva, Koskenvuo Juha, Karvonen Jukka, Ovaska Jari
Department of Surgery, Turku University Central Hospital, Kiinamyllynkatu 4-8, 20520 Turku, Finland.
Surg Laparosc Endosc Percutan Tech. 2007 Apr;17(2):73-8. doi: 10.1097/SLE.0b013e31803bb500.
Laparoscopic fundoplication is a routine surgical approach in the treatment of moderate or severe gastro-esophageal reflux disease. However, there are still contradictions regarding supraesophageal symptoms as an indication for surgery. The aim of this study was to determine the subjective symptomatic outcome and objective laryngeal findings after antireflux surgery in patients with pH monitoring proven reflux laryngitis. Between 1998 and 2002, 40 patients with reflux laryngitis underwent laparoscopic Nissen fundoplication. Patients were referred to surgery and followed-up by a specialist in otorhinolaryngology. Subjective symptoms were collected by a structured questionnaire at a median follow-up of 42 months. The objective laryngeal findings improved from the preoperative situation; at 12 months after surgery, the otorhinolaryngeal status was improved in 92.3% (n=24) of the patients. However, only 38.5% (n=10) of these patients evaluated an improvement in their voice quality. Of all, 62.5% (n=25) of the patients reported no or only mild cough or voice hoarseness symptoms postoperatively, 22.5% (n=9) had moderate symptoms, and 15.0% (n=6) suffered from difficult supraesophageal symptoms. Ninety-five percent of the patients regarded the result of their surgery excellent, good, or satisfactory. Of all, 82.5% (n=33) of the patients would still choose surgery, 7.5% (n=3) would abstain from surgery, and 10% (n=4) of the patients were hesitant about their choice. For patients suffering from supraesophageal symptoms of gastro-esophageal reflux disease with objective evidence of pharyngeal acid exposure, laparoscopic Nissen fundoplication provides a good and alternative adding to current treatment.
腹腔镜胃底折叠术是治疗中重度胃食管反流病的常规手术方法。然而,对于将食管上症状作为手术指征仍存在争议。本研究的目的是确定经pH监测证实为反流性喉炎的患者在抗反流手术后的主观症状结果和客观喉部检查结果。1998年至2002年期间,40例反流性喉炎患者接受了腹腔镜尼森胃底折叠术。患者被转诊接受手术,并由耳鼻喉科专家进行随访。在中位随访42个月时,通过结构化问卷收集主观症状。客观喉部检查结果较术前有所改善;术后12个月时,92.3%(n = 24)的患者耳鼻喉状况得到改善。然而,这些患者中只有38.5%(n = 10)评估声音质量有所改善。总体而言,62.5%(n = 25)的患者术后报告无咳嗽或声音嘶哑症状或仅有轻微症状,22.5%(n = 9)有中度症状,15.0%(n = 6)患有严重的食管上症状。95%的患者认为手术结果优秀、良好或满意。总体而言,82.5%(n = 33)的患者仍会选择手术,7.5%(n = 3)会放弃手术,10%(n = 4)的患者对自己的选择犹豫不决。对于患有胃食管反流病食管上症状且有咽酸暴露客观证据的患者,腹腔镜尼森胃底折叠术是目前治疗方法的一种良好替代方法。