van der Schroeff M P, de Ru J A, Slootweg P J
Department of Otolaryngology/Head and Neck Surgery, Erasmus Medical Center Rotterdam, The Netherlands.
B-ENT. 2007;3(1):21-5.
Metastasizing pleomorphic adenoma of the parotid gland. We present a case of metastasizing pleomorphic adenoma (MPA). The patient died in 2002 at the age of 64 years, following on an initial diagnosis of a pleomorphic adenoma of the right parotid gland at the age of nineteen, multiple local recurrences and finally rib metastases. Histological examination of the excised tissue from the parotid gland and the metastases showed it to be a pleomorphic adenoma without any signs of malignancy, although the metastatic deposits consisted mostly of a myoepithelial component. Both in our case as in most of the literature, MPA follows a probable incomplete removal of the first tumour. We conclude that the first operation is of great importance for the prevention of late recurrences and metastatic spread.
腮腺转移性多形性腺瘤。我们报告一例腮腺转移性多形性腺瘤(MPA)。该患者于2002年去世,享年64岁,最初在19岁时被诊断为右腮腺多形性腺瘤,经历多次局部复发,最终出现肋骨转移。对腮腺及转移灶切除组织的组织学检查显示,其为多形性腺瘤,无任何恶性迹象,尽管转移灶主要由肌上皮成分组成。在我们的病例以及大多数文献报道中,MPA可能是由于首次肿瘤切除不完全所致。我们得出结论,首次手术对于预防晚期复发和转移扩散至关重要。