Shimizu Naoki, Okamoto Hideyuki, Koyama Shinji, Yane Katsunari, Hosoi Hiroshi, Okamura Ryuji
Department of Otorhinolaryngology, Yamato Takada Municipal Hospital, 1-1 Isonokita, Yamatotakada, Nara 635-8501, Japan.
Auris Nasus Larynx. 2008 Dec;35(4):572-5. doi: 10.1016/j.anl.2007.11.007. Epub 2008 Feb 12.
Laryngeal carcinoma is usually encountered in smoker men, and thyroid carcinoma is sometimes discovered incidentally during treatment for these patients. However, this coexistence of malignancies could occur in non-smoker female. We report an unusual case of multiple primary malignancies in the larynx and the thyroid gland. The laryngeal carcinoma was suspected to be related to the malignant transformation of the papillomas. The case suggests the importance of meticulous examination in the head and neck region for treatment of cervical metastatic lymph nodes with negative cytology in non-smoker female.
喉癌通常见于吸烟男性，而甲状腺癌有时在这些患者的治疗过程中被偶然发现。然而，这种恶性肿瘤的共存也可能发生在不吸烟的女性身上。我们报告一例喉和甲状腺多发原发性恶性肿瘤的罕见病例。喉癌被怀疑与乳头状瘤的恶变有关。该病例提示，对于不吸烟女性颈部转移性淋巴结细胞学检查阴性的患者，对头颈部进行细致检查以进行治疗具有重要意义。
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