Gbakima A A, Pessima J, Sahr F
Tropical Diseases Research Unit, Department of Biological Sciences, Njala University College.
Afr J Health Sci. 1996 May;3(2):37-40.
A total of 302 people were examined in 3 villages in the Moyamba District, Sierra Leone of microfilaria (mf) and clinical signs of Wuchereria bancrofti infection. Mf rates were 34.5% and 31.8% for Bonganema, Old Mosongo and Pelewahun respectively. The average mf rate of those examined was 34.8%. Analysed by age and sex, the highest mf rates were observed in males of age >/=21 years (46 - 56%). The relative risk of infection was significantly lower (P<0.000) for 5-10 year olds than 11+ year old individuals. Clinical studies of 284 individuals of age >/=11 years showed that recurrent fever was the commonest clinical sign observed and the rate was 5.9%. For the ages >/=41 years, the recurrent fever was 10%. The average hydrocele and elephantiasis rates were 2.5% and 1.1% respectively. For the ages >/=41 years, the hydrocele and elephantiasis rates were 4% and 3% respectively, indicating that Filariasis is an important public health problem in the area. Annual mass treatment of the study area residents with ivermectin for onchocerciasis has begun. Ivermectin has been reported to be effective for control of lymphatic Filariasis. The displacement of the population due to the undeclared war in the area will certainly negate the effects of the mass treatment programme.
在塞拉利昂莫扬巴区的3个村庄，对总共302人进行了班氏吴策线虫感染的微丝蚴（mf）和临床症状检查。邦加内马、老莫松戈和佩莱瓦洪的mf感染率分别为34.5%和31.8%。受检者的平均mf感染率为34.8%。按年龄和性别分析，mf感染率最高的是年龄≥21岁的男性（46 - 56%）。5 - 10岁儿童的感染相对风险显著低于11岁及以上个体（P<0.000）。对284名年龄≥11岁个体的临床研究表明，反复发热是最常见的临床症状，发生率为5.9%。对于年龄≥41岁者，反复发热率为10%。鞘膜积液和象皮肿的平均发生率分别为2.5%和1.1%。对于年龄≥41岁者，鞘膜积液和象皮肿的发生率分别为4%和3%，这表明丝虫病是该地区一个重要的公共卫生问题。已开始对研究地区居民每年进行一次伊维菌素群体治疗盘尾丝虫病。据报道，伊维菌素对控制淋巴丝虫病有效。该地区因未宣战的战争导致的人口流离失所肯定会抵消群体治疗方案的效果。
