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Something old, something new: BDNF-induced neuron survival requires TRPC channel function.

作者信息

Sossin Wayne S, Barker Philip A

出版信息

Nat Neurosci. 2007 May;10(5):537-8. doi: 10.1038/nn0507-537.

DOI:10.1038/nn0507-537
PMID:17453053
Abstract
摘要

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1
Something old, something new: BDNF-induced neuron survival requires TRPC channel function.旧物新用：脑源性神经营养因子诱导的神经元存活需要瞬时受体电位通道功能。
Nat Neurosci. 2007 May;10(5):537-8. doi: 10.1038/nn0507-537.
2
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor.瞬时受体电位通道在脑源性神经营养因子对神经生长锥的引导中起关键作用。
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3
TRPC channels promote cerebellar granule neuron survival.瞬时受体电位通道促进小脑颗粒神经元存活。
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4
[Canonical transient receptor potential ion channel is involved in sodium nitroprusside-induced apoptosis of cultured rat hippocampal neurons].[典型瞬时受体电位离子通道参与硝普钠诱导的原代培养大鼠海马神经元凋亡]
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Acceleration of methylmercury-induced cell death of rat cerebellar neurons by brain-derived neurotrophic factor in vitro.脑源性神经营养因子在体外加速甲基汞诱导的大鼠小脑神经元细胞死亡
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6
In-vitro effects of brain-derived neurotrophic factor on neural progenitor/stem cells from rat hippocampus.脑源性神经营养因子对大鼠海马神经祖细胞/干细胞的体外作用
Neuroreport. 2009 Feb 18;20(3):295-300. doi: 10.1097/WNR.0b013e32832000c8.
7
BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype.脑源性神经营养因子和细胞外基质调节小鼠神经球衍生细胞向γ-氨基丁酸能神经元表型的分化。
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8
Protective effects of brain-derived neurotrophic factor against neurotoxicity of 3-nitropropionic acid in rat cortical neurons.脑源性神经营养因子对3-硝基丙酸所致大鼠皮质神经元神经毒性的保护作用
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Pitx3-transfected astrocytes secrete brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor and protect dopamine neurons in mesencephalon cultures.转染Pitx3的星形胶质细胞分泌脑源性神经营养因子和胶质细胞系源性神经营养因子，并保护中脑培养物中的多巴胺能神经元。
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BDNF increases survival of retinal dopaminergic neurons after prenatal compromise.脑源性神经营养因子可提高产前损伤后视网膜多巴胺能神经元的存活率。
Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1282-9. doi: 10.1167/iovs.07-0521.

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General anesthetic agents induce neurotoxicity through astrocytes.
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Int J Mol Sci. 2021 Feb 19;22(4):2074. doi: 10.3390/ijms22042074.
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Dexmedetomidine improves cognition after carotid endarterectomy by inhibiting cerebral inflammation and enhancing brain-derived neurotrophic factor expression.右美托咪定通过抑制脑内炎症反应和增强脑源性神经营养因子表达来改善颈动脉内膜切除术后的认知功能。
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HERV-W env regulates calcium influx via activating TRPC3 channel together with depressing DISC1 in human neuroblastoma cells.人类内源性逆转录病毒 W 的 env 蛋白通过与 DISC1 共同作用抑制来激活 TRPC3 通道调节钙离子内流。
J Neurovirol. 2019 Feb;25(1):101-113. doi: 10.1007/s13365-018-0692-7. Epub 2018 Nov 5.
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Insufficient Astrocyte-Derived Brain-Derived Neurotrophic Factor Contributes to Propofol-Induced Neuron Death Through Akt/Glycogen Synthase Kinase 3β/Mitochondrial Fission Pathway.星形胶质细胞源性脑源性神经营养因子不足通过Akt/糖原合酶激酶3β/线粒体分裂途径导致丙泊酚诱导的神经元死亡。
Anesth Analg. 2017 Jul;125(1):241-254. doi: 10.1213/ANE.0000000000002137.
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The Role of TRPC6 in the Neuroprotection of Calycosin Against Cerebral Ischemic Injury.TRPC6 在毛蕊异黄酮对脑缺血损伤的神经保护作用中的角色。
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Cell Signaling and Differential Protein Expression in Neuronal Differentiation of Bone Marrow Mesenchymal Stem Cells with Hypermethylated Salvador/Warts/Hippo (SWH) Pathway Genes.骨髓间充质干细胞神经元分化过程中细胞信号传导及差异蛋白表达与萨尔瓦多/疣/河马（SWH）信号通路基因高甲基化的关系
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