Lamont P J, Johnston H M, Berdoukas V A
Department of Paediatric Neurology, Prince of Wales Childrens Hospital, Sydney, Australia.
Neurology. 1991 Dec;41(12):1928-31. doi: 10.1212/wnl.41.12.1928.
Between 1987 and 1989, we plasmapheresed six children with Guillain-Barré syndrome (GBS). None of the children could walk independently at the start of the treatment, and one was being ventilated. Five patients showed clinical improvement during pheresis, and no significant side effects occurred. The median time from onset of weakness to independent walking for these six children was 17 days. This compares with 43 days for 18 children with GBS in this institution who were given supportive measures only.
1987年至1989年间，我们对6例吉兰-巴雷综合征（GBS）患儿进行了血浆置换。治疗开始时，所有患儿均无法独立行走，其中1例需要机械通气。5例患儿在血浆置换过程中临床症状改善，且未出现明显副作用。这6例患儿从肌无力发作到独立行走的中位时间为17天。相比之下，该机构中仅接受支持治疗的18例GBS患儿达到独立行走的中位时间为43天。
