Neurology. 1985 Aug;35(8):1096-104.
We compared plasmapheresis with conventional therapy in 245 patients with the Guillain-Barré syndrome of recent onset. Statistically significant differences, favoring the plasmapheresis group, were found in terms of improvement at 4 weeks, time to improve one clinical grade, time to independent walking, and outcome at 6 months. Plasmapheresis was not effective for all patients, but was particularly effective for patients who received this treatment within 7 days of onset and for patients who required mechanical ventilation after entry into the study. Plasmapheresis appears to be of benefit in patients with Guillain-Barré syndrome of recent onset.
我们将245例近期发病的吉兰-巴雷综合征患者的血浆置换疗法与传统疗法进行了比较。在4周时的改善情况、改善一个临床等级所需时间、独立行走所需时间以及6个月时的结局方面，发现了有利于血浆置换组的具有统计学意义的差异。血浆置换并非对所有患者都有效，但对于发病7天内接受该治疗的患者以及研究入组后需要机械通气的患者特别有效。血浆置换似乎对近期发病的吉兰-巴雷综合征患者有益。
