Delmaire C, Krainik A, Lethuc V, Reyns N, Duffau H, Capelle L, Lehéricy S
Services de Neuroradiologie, CHRU Lille, Hôpital Roger Salengro, boulevard du Pr Laine, 59800 Lille.
J Radiol. 2007 Mar;88(3 Pt 2):497-509. doi: 10.1016/s0221-0363(07)89849-0.
Brain functional MRI (fMRI) provides an indirect mapping of cerebral activity, based on the detection of local changes in blood flow and oxygenation levels that are associated with neuronal activity (BOLD contrast). fMRI allows noninvasive studies of normal and pathological aspects of the brain's functional organization. It is based on the comparison of two or more cognitive states. Echoplanar imaging is the technique of choice, providing the quickest study of the entire brain. Activation maps are calculated from a statistical analysis of the local signal changes. fMRI has become one of the most widely used functional imaging techniques in neuroscience. In clinical practice, fMRI can identify eloquent areas involved in motor and language functions in surgical patients and can evaluate the risk of postoperative neurological deficit.
脑功能磁共振成像（fMRI）基于检测与神经元活动相关的局部血流和氧合水平变化（血氧水平依赖对比），提供大脑活动的间接映射。fMRI允许对大脑功能组织的正常和病理方面进行非侵入性研究。它基于两种或更多认知状态的比较。回波平面成像是首选技术，能对整个大脑进行最快的研究。激活图是根据局部信号变化的统计分析计算得出的。fMRI已成为神经科学中使用最广泛的功能成像技术之一。在临床实践中，fMRI可以识别手术患者运动和语言功能相关的明确区域，并评估术后神经功能缺损的风险。
