膜性肾病：何时以及如何治疗。
Membranous nephropathy: when and how to treat.
作者信息
Lai K N
机构信息
Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong.
出版信息
Kidney Int. 2007 May;71(9):841-3. doi: 10.1038/sj.ki.5002201.
PMID:17457329
Abstract
The treatment of idiopathic membranous nephropathy is heavily debated because of wide variation in outcome. A rational treatment strategy is needed to appropriately administer conservative treatment to the low-risk group but immunosuppressive therapy to those with medium or high risk of renal deterioration. Currently, combinations of steroids with alkylating agents are best studied. Newer forms of immunosuppressive treatment are currently under study.
摘要
由于特发性膜性肾病的治疗结果差异很大，其治疗方法备受争议。需要一种合理的治疗策略，以便对低风险组进行适当的保守治疗，而对有中度或高度肾脏恶化风险的患者进行免疫抑制治疗。目前，对类固醇与烷化剂的联合使用研究得最为充分。新型免疫抑制治疗方法目前正在研究中。
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