Tuncer Bilge, Babacan Avni, Arslan Mustafa
Gazi University Faculty of Medicine, Department of Anesthesiology and Reanimation, Ankara, Turkey.
Agri. 2007 Jan;19(1):42-9.
The purpose of this study was to determine the effectiveness of intraarticular (ia) bupivacaine and tramadol injection and preemptive intraarticular tramadol in providing pain control after arthroscopic knee surgery. Following local research ethics committee approval, 60 patients were assigned in a randomized manner into three groups: Group I received ia 20 ml of 0.25 % bupivacaine at the end of the operation, Group II received ia 20 ml of 0.25 % bupivacaine and 100 mg of tramadol at the end of the operation and Group III received ia 100 mg of tramadol diluted in 20 ml of saline solution 30 minutes before skin inscision and 20 ml of 0.25% bupivacaine at the end of the operation as well. Analgesic duration, total analgesic consumption and postoperative VAS pain scores recorded at rest and with movement were significantly lower and patient satisfaction was significantly higher in Group II and III, compared to Group I. Total analgesic consumption and the number of patients requiring supplementary analgesics were significantly lower in the preemptive tramadol group compared to the postoperative tramadol group. In conclusion, preemptive ia tramadol provided effective and reliable pain control after artroscopic knee surgeries and may be preferred to postoperative administration.
本研究的目的是确定关节腔内注射布比卡因和曲马多以及预防性关节腔内注射曲马多在膝关节镜手术后提供疼痛控制的有效性。经当地研究伦理委员会批准,60例患者被随机分为三组:第一组在手术结束时接受关节腔内注射20 ml 0.25%布比卡因;第二组在手术结束时接受关节腔内注射20 ml 0.25%布比卡因和100 mg曲马多;第三组在皮肤切开前30分钟接受关节腔内注射用20 ml生理盐水稀释的100 mg曲马多,并在手术结束时接受关节腔内注射20 ml 0.25%布比卡因。与第一组相比,第二组和第三组记录的镇痛持续时间、总镇痛药物消耗量以及静息和活动时的术后视觉模拟评分法(VAS)疼痛评分显著更低,患者满意度显著更高。与术后注射曲马多组相比,预防性注射曲马多组的总镇痛药物消耗量和需要补充镇痛药物的患者数量显著更低。总之,预防性关节腔内注射曲马多在膝关节镜手术后提供了有效且可靠的疼痛控制,可能比术后给药更可取。
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