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[体外冲击波碎石术后输尿管狭窄。病例报告及现代体外冲击波碎石术罕见副作用谱概述]

[Ureteral stricture after extracorporeal shock wave lithotripsy. Case report and overview of the spectrum of rare side effects of modern ESWL treatment].

作者信息

Finter F, Rinnab L, Simon J, Volkmer B, Hautmann R, Kuefer R

机构信息

Abteilung für Urologie und Kinderurologie, Urologische Universitätsklinik, Universität, 89075, Ulm.

出版信息

Urologe A. 2007 Jul;46(7):769-72. doi: 10.1007/s00120-007-1334-5.

Abstract

Extracorporeal shock wave lithotripsy (ESWL) is considered a very safe and noninvasive procedure for the treatment of urolithiasis. Achievements in the technical development of recent decades resulted in a continuous reduction of side effects. One of our patients, a woman with cystinuria, developed a temporary ureteral stricture after several sessions of ESWL. Encouraged by this observation we set out to explore--based on a MEDLINE literature search--published reports of more severe side effects observed in modern ESWL therapy. Besides hydronephrosis and renal colic the most common side effects were renal and perirenal hematomas in up to 4% in the larger series. Uncommon extrarenal complications are described mostly in case reports, which are also outlined in this report. The injury of visceral organs (liver, spleen, gut, pancreas) was published most frequently. A rupture or dissection of an abdominal aortic aneurysm as an outstanding serious complication was also reported several times. Taking obvious and well-known contraindications into consideration and carefully preparing the patients for the therapy (i.e., checking hemostasis, drug history), ESWL is a very safe procedure with a low risk of serious complications. Yet, postoperative clinical and ultrasound monitoring seems to be essential especially with respect to the increasing numbers of outpatient procedures.

摘要

体外冲击波碎石术(ESWL)被认为是治疗尿石症非常安全且无创的方法。近几十年来技术发展所取得的成果使得副作用持续减少。我们的一位胱氨酸尿症女性患者在接受多次ESWL治疗后出现了暂时性输尿管狭窄。受此观察结果的鼓舞,我们基于医学文献数据库(MEDLINE)检索,着手探究现代ESWL治疗中观察到的更严重副作用的已发表报告。除肾积水和肾绞痛外,在较大规模的系列研究中,最常见的副作用是肾和肾周血肿,发生率高达4%。罕见的肾外并发症大多在病例报告中有所描述,本报告也对此进行了概述。其中,内脏器官(肝脏、脾脏、肠道、胰腺)损伤的报道最为频繁。腹主动脉瘤破裂或夹层形成作为一种极为严重的并发症也有多次报道。考虑到明显且众所周知的禁忌症,并为患者进行仔细的治疗准备(如检查止血情况、用药史),ESWL是一种非常安全的方法,严重并发症风险较低。然而,术后临床及超声监测似乎至关重要,尤其是考虑到门诊手术数量不断增加的情况。

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