(Z)-和(E)-γ-溴代高烯丙醇向2,4,5,6-四取代四氢吡喃的高度立体选择性普林斯环化反应
Highly stereoselective prins cyclization of (Z)- and (E)-gamma-brominated homoallylic alcohols to 2,4,5,6-tetrasubstituted tetrahydropyrans.
作者信息
Liu Feng, Loh Teck-Peng
机构信息
Division of Chemistry and Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore 637616.
出版信息
Org Lett. 2007 May 24;9(11):2063-6. doi: 10.1021/ol070506n. Epub 2007 Apr 26.
PMID:17458976
Abstract
An efficient method has been developed to construct 2,6-cis-4,5-dibromo-tetrasubstituted tetrahydropyran (THP) rings with well-controlled stereochemistry in moderate to high yields.
摘要
已开发出一种高效方法，用于构建具有良好立体化学控制且产率适中至较高的2,6-顺式-4,5-二溴四取代四氢吡喃（THP）环。
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