食物恐新症在人类中表现出可遗传的变异。

Food neophobia shows heritable variation in humans.

作者信息

Knaapila Antti, Tuorila Hely, Silventoinen Karri, Keskitalo Kaisu, Kallela Mikko, Wessman Maija, Peltonen Leena, Cherkas Lynn F, Spector Tim D, Perola Markus

机构信息

Department of Food Technology, University of Helsinki, FI-00014, University of Helsinki, Helsinki, Finland.

出版信息

Physiol Behav. 2007 Aug 15;91(5):573-8. doi: 10.1016/j.physbeh.2007.03.019. Epub 2007 Mar 30.

DOI:10.1016/j.physbeh.2007.03.019

PMID:17459432

Abstract

Food neophobia refers to reluctance to eat unfamiliar foods. We determined the heritability of food neophobia in a family and a twin sample. The family sample consisted of 28 Finnish families (105 females, 50 males, aged 18-78 years, mean age 49 years) and the twin sample of 468 British female twin pairs (211 monozygous and 257 dizygous pairs, aged 17-82 years, mean age 55 years). Food neophobia was measured using the ten-item Food Neophobia Scale (FNS) questionnaire, and its internationally validated six-item modification. The heritability estimate for food neophobia was 69 and 66% in Finnish families (h(2)) and 67 and 66% in British female twins (a(2)+d(2)) using the ten- and six-item versions of the FNS, respectively. The results from both populations suggest that about two thirds of variation in food neophobia is genetically determined.

摘要

食物恐新症是指不愿食用不熟悉的食物。我们在一个家庭样本和一个双胞胎样本中确定了食物恐新症的遗传力。家庭样本包括28个芬兰家庭（105名女性，50名男性，年龄在18至78岁之间，平均年龄49岁），双胞胎样本包括468对英国女性双胞胎（211对同卵双胞胎和257对异卵双胞胎，年龄在17至82岁之间，平均年龄55岁）。使用十项食物恐新症量表（FNS）问卷及其经过国际验证的六项修改版来测量食物恐新症。分别使用FNS的十项版和六项版，芬兰家庭中食物恐新症的遗传力估计值为69%和66%（h(2)），英国女性双胞胎中为67%和66%（a(2)+d(2)）。来自这两个人群的结果表明，食物恐新症约三分之二的变异是由基因决定的。