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Using blood brain barrier disruption by methamphetamine for drug delivery.

作者信息

Kast R E

出版信息

J Neurooncol. 2007 Oct;85(1):109-10. doi: 10.1007/s11060-007-9389-0. Epub 2007 Apr 27.

DOI:10.1007/s11060-007-9389-0
PMID:17464448
Abstract
摘要

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Methamphetamine enhances caveolar transport of therapeutic agents across the rodent blood-brain barrier.甲基苯丙胺增强治疗药物在啮齿动物血脑屏障中的囊泡转运。
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Morphine modulates doxorubicin uptake and improves efficacy of chemotherapy in an intracranial xenograft model of human glioblastoma.

本文引用的文献

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Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group.在复发性恶性胶质瘤中直接脑内注射cintredekin besudotox(IL13-PE38QQR):cintredekin besudotox脑实质内研究组的报告
J Clin Oncol. 2007 Mar 1;25(7):837-44. doi: 10.1200/JCO.2006.08.1117.
2
Alterations in blood-brain barrier function by morphine and methamphetamine.吗啡和甲基苯丙胺对血脑屏障功能的影响。
Ann N Y Acad Sci. 2006 Aug;1074:198-224. doi: 10.1196/annals.1369.020.
3
High doses of methamphetamine that cause disruption of the blood-brain barrier in limbic regions produce extensive neuronal degeneration in mouse hippocampus.
吗啡调节阿霉素摄取并提高人胶质母细胞瘤颅内异种移植模型中的化疗疗效。
Am J Cancer Res. 2016 Feb 15;6(3):639-48. eCollection 2016.
4
The blood-brain barrier and methamphetamine: open sesame?血脑屏障与甲基苯丙胺:芝麻开门?
Front Neurosci. 2015 May 5;9:156. doi: 10.3389/fnins.2015.00156. eCollection 2015.
5
Morphine facilitates doxorubicin penetration in the central nervous system: a new prospect for therapy of brain tumors.
J Neurooncol. 2011 Sep;104(2):619-20. doi: 10.1007/s11060-010-0518-9. Epub 2011 Jan 14.
6
Three paths to better tyrosine kinase inhibition behind the blood-brain barrier in treating chronic myelogenous leukemia and glioblastoma with imatinib.三种途径改善血脑屏障背后的酪氨酸激酶抑制作用,以伊马替尼治疗慢性髓性白血病和胶质母细胞瘤。
Transl Oncol. 2010 Feb;3(1):13-5. doi: 10.1593/tlo.09280.
7
Use of FDA approved methamphetamine to allow adjunctive use of methylnaltrexone to mediate core anti-growth factor signaling effects in glioblastoma.
J Neurooncol. 2009 Sep;94(2):163-7. doi: 10.1007/s11060-009-9863-y. Epub 2009 Mar 26.
高剂量甲基苯丙胺会导致边缘区域血脑屏障遭到破坏,进而在小鼠海马体中引发广泛的神经元退化。
Synapse. 2006 Dec 1;60(7):521-32. doi: 10.1002/syn.20324.
4
Delivery of chemotherapy and antibodies across the blood-brain barrier and the role of chemoprotection, in primary and metastatic brain tumors: report of the Eleventh Annual Blood-Brain Barrier Consortium meeting.化疗药物和抗体透过血脑屏障的递送以及化学保护在原发性和转移性脑肿瘤中的作用:第十一届血脑屏障联盟年会报告
J Neurooncol. 2007 Jan;81(1):81-91. doi: 10.1007/s11060-006-9209-y. Epub 2006 Jul 21.
5
Causes and consequences of methamphetamine and MDMA toxicity.甲基苯丙胺和摇头丸中毒的原因及后果。
AAPS J. 2006 May 12;8(2):E337-47. doi: 10.1007/BF02854904.
6
Methamphetamine induces AP-1 and NF-kappaB binding and transactivation in human brain endothelial cells.甲基苯丙胺在人脑海马内皮细胞中诱导AP-1和NF-κB结合及反式激活。
J Neurosci Res. 2001 Nov 15;66(4):583-91. doi: 10.1002/jnr.1248.