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Morphine facilitates doxorubicin penetration in the central nervous system: a new prospect for therapy of brain tumors.

作者信息

Sardi Iacopo

出版信息

J Neurooncol. 2011 Sep;104(2):619-20. doi: 10.1007/s11060-010-0518-9. Epub 2011 Jan 14.

DOI:10.1007/s11060-010-0518-9
PMID:21234643
Abstract
摘要

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Cancer Chemother Pharmacol. 2011 Jun;67(6):1333-40. doi: 10.1007/s00280-010-1429-3. Epub 2010 Aug 25.
2
Effect of chronic exposure to morphine on the rat blood-brain barrier: focus on the P-glycoprotein.长期暴露于吗啡对大鼠血脑屏障的影响:聚焦于P-糖蛋白。
J Neurochem. 2008 Nov;107(3):647-57. doi: 10.1111/j.1471-4159.2008.05647.x. Epub 2008 Aug 30.
3
PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model.
血脑屏障与乳腺癌耐药蛋白:中枢神经系统肿瘤和神经退行性疾病治疗的限制因素
Anticancer Agents Med Chem. 2016;16(7):810-5. doi: 10.2174/1871520616666151120121928.
4
The blood-brain barrier and methamphetamine: open sesame?血脑屏障与甲基苯丙胺:芝麻开门?
Front Neurosci. 2015 May 5;9:156. doi: 10.3389/fnins.2015.00156. eCollection 2015.
5
The Use of Anthracyclines for Therapy of CNS Tumors.蒽环类药物在中枢神经系统肿瘤治疗中的应用。
Anticancer Agents Med Chem. 2015;15(6):721-7. doi: 10.2174/1871520615666150407155319.
6
Pharmacological modulation of blood-brain barrier increases permeability of doxorubicin into the rat brain.药物调节血脑屏障增加阿霉素向大鼠脑内的通透性。
Am J Cancer Res. 2013 Aug 14;3(4):424-32. eCollection 2013.
磷酸二酯酶5抑制剂可增强大鼠脑肿瘤模型中的肿瘤渗透性及化疗疗效。
Brain Res. 2008 Sep 16;1230:290-302. doi: 10.1016/j.brainres.2008.06.122. Epub 2008 Jul 14.
4
Using blood brain barrier disruption by methamphetamine for drug delivery.利用甲基苯丙胺破坏血脑屏障进行药物递送。
J Neurooncol. 2007 Oct;85(1):109-10. doi: 10.1007/s11060-007-9389-0. Epub 2007 Apr 27.
5
Alterations in blood-brain barrier function by morphine and methamphetamine.吗啡和甲基苯丙胺对血脑屏障功能的影响。
Ann N Y Acad Sci. 2006 Aug;1074:198-224. doi: 10.1196/annals.1369.020.
6
Local delivery of doxorubicin for the treatment of malignant brain tumors in rats.多柔比星局部给药治疗大鼠恶性脑肿瘤
Anticancer Res. 2005 Nov-Dec;25(6B):3825-31.
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Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases.药物外排转运体在脑内药物处置及脑部疾病治疗中的作用。
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Intratumoral doxorubicin in patients with malignant brain gliomas.恶性脑胶质瘤患者瘤内注射阿霉素
Am J Clin Oncol. 2002 Feb;25(1):60-4. doi: 10.1097/00000421-200202000-00013.