Dickson Brendan C, Fornasier Victor L, Streutker Catherine J, Stewart Robert J
Division of Pathology, University of Toronto, St. Michael's Hospital, Toronto, Ontario, Canada.
Can J Urol. 2007 Apr;14(2):3526-8.
We present the case of a 78-year-old male who presented to clinic for follow-up of a papillary transitional cell carcinoma of the urinary bladder. Notably, the patient also had a history of colorectal resection for an adenocarcinoma. The follow-up appointment revealed left hydronephrosis with evidence of a distal ureteric stricture. Cytology and biopsy from the ureter subsequently disclosed the presence of malignant cells that were originally thought to be of urothelial origin. Upon surgical resection the lesion was found to be an adenocarcinoma, morphologically consistent with a metastasis from the patient's primary colonic adenocarcinoma. This case illustrates a diagnostically challenging situation, with metastatic colonic carcinoma to the ureter occurring in a patient with two previously documented malignancies.
我们报告了一例78岁男性患者的病例，该患者因膀胱乳头状移行细胞癌前来诊所进行随访。值得注意的是，该患者既往有因腺癌接受结肠切除术的病史。随访预约检查发现左肾积水，并伴有远端输尿管狭窄的迹象。随后对输尿管进行的细胞学检查和活检显示存在恶性细胞，最初认为这些细胞起源于尿路上皮。手术切除后发现该病变为腺癌，形态学上与患者原发性结肠腺癌的转移灶一致。该病例说明了一种具有诊断挑战性的情况，即输尿管转移性结肠癌发生在一名先前有两种确诊恶性肿瘤的患者身上。
