Nikolaos Ferakis, Panagiotis Anastasopoulos, Konstantinos Bouropoulos, Vassilios Samaras, Iraklis Poulias
Department of Urology, Korgialenio-Benakio Hellenic Red Cross Hospital, Athanasaki 1, 11526 Athens, Greece.
Department of Pathology, Korgialenio-Benakio Hellenic Red Cross Hospital, Athanasaki 1, 11526 Athens, Greece.
Case Rep Urol. 2014;2014:196425. doi: 10.1155/2014/196425. Epub 2014 Mar 4.
Carcinomas arising from organs neighbouring the ureter can directly infiltrate the ureter. Distant ureteral metastasis from colon adenocarcinoma is extremely rare and usually an incidental finding in performed autopsies. We report a case of a right ureteral metastasis in a 65-year-old Caucasian male with a history of rectal cancer for which he had been treated 4 years before. He presented with asymptomatic moderate right hydronephrosis. The patient underwent a right nephroureterectomy. Histology of the ureter revealed transmural adenocarcinoma with infiltration of the mucosa. Infiltration of the muscular coat of the bladder was found 2 years later. Thus, cystectomy and left ureterocutaneostomy were performed. The patient died 6 months later due to toxic megacolon during chemotherapy. The differential diagnosis of ureteral adenocarcinoma, especially in patients with previous history of colon adenocarcinoma, should include the possibility of distant metastasis from the primary colonic tumor.
起源于输尿管邻近器官的癌可直接浸润输尿管。结肠腺癌远处转移至输尿管极为罕见，通常是在尸检时偶然发现。我们报告一例65岁白种男性右输尿管转移癌病例，该患者有直肠癌病史，4年前接受过治疗。他表现为无症状的中度右肾积水。患者接受了右肾输尿管切除术。输尿管组织学检查显示为透壁腺癌伴黏膜浸润。2年后发现膀胱肌层浸润。因此，进行了膀胱切除术和左输尿管皮肤造口术。患者在化疗期间因中毒性巨结肠于6个月后死亡。输尿管腺癌的鉴别诊断，尤其是有结肠腺癌病史的患者，应包括原发性结肠肿瘤远处转移的可能性。
