Liu Renyi, Asmussen Marjorie A
Department of Genetics, University of Georgia, Athens, GA 30602, USA.
Theor Popul Biol. 2007 Jun;71(4):445-53. doi: 10.1016/j.tpb.2007.03.008. Epub 2007 Mar 28.
We develop a mathematical model to delimit the role of natural selection in maintaining nuclear and cytoplasmic polymorphisms in selfing populations. We provide explicit time-dependent solutions for joint cytonuclear frequencies under any combination of constant fertility, viability, and gametic selection and exact analytical conditions for the maintenance of polymorphisms under joint cytonuclear selection. The equilibrium structure is determined by the relative magnitude of echo fitnesses, defined as the rate at which individuals survive and produce offspring with their own genotype. Both nuclear and cytoplasmic polymorphisms can be maintained under biologically meaningful conditions, although the majority of the parameter combinations will lead to fixation. The theoretical framework developed here should be very useful in formally dissecting the form and strength of selection on cytonuclear genotypes in populations with negligible levels of outcrossing.
我们构建了一个数学模型，以界定自然选择在自交种群中维持核与细胞质多态性方面所起的作用。我们给出了在恒定育性、生存力和配子选择的任何组合下联合细胞核-细胞质频率的明确时间依赖解，以及在联合细胞核-细胞质选择下维持多态性的精确分析条件。平衡结构由回声适合度的相对大小决定，回声适合度定义为个体存活并产生与其自身基因型相同后代的速率。尽管大多数参数组合会导致固定化，但在生物学上有意义的条件下，核与细胞质多态性都可以维持。这里开发的理论框架对于正式剖析杂交水平可忽略不计的种群中对细胞核-细胞质基因型的选择形式和强度应该非常有用。
