晚期癌症患者的睡眠质量

Sleep quality in advanced cancer patients.

作者信息

Mystakidou Kyriaki, Parpa Efi, Tsilika Eleni, Pathiaki Maria, Patiraki Elisabeth, Galanos Antonis, Vlahos Lambros

机构信息

Pain Relief and Palliative Care Unit, Department of Radiology, Areteion Hospital, School of Medicine, University of Athens, Athens, Greece.

出版信息

J Psychosom Res. 2007 May;62(5):527-33. doi: 10.1016/j.jpsychores.2006.11.008.

DOI:10.1016/j.jpsychores.2006.11.008

PMID:17467407

Abstract

OBJECTIVE

The objective of this study was to evaluate the sleep quality of advanced cancer patients and its relationship with pain, depression, and hopelessness.

METHODS

The participants were 102 advanced cancer patients who were on palliative treatment. Patients completed a sleep quality instrument, the Pittsburgh Sleep Quality Index (PSQI); a pain assessment tool, the Greek Brief Pain Inventory; a self-report measure of depression, the Beck Depression Inventory; and, finally, the Beck Hopelessness Scale.

RESULTS

Multiple regression analyses (forward method) have shown that hopelessness (P=.003), "interference of pain with mood" (P<.0005), and strong opioids (P=.010) seemed to influence patients' sleep quality (PSOI). In an additional regression analysis (enter method), the PSQI is significantly related to opioids (P=.013), hopelessness (P=.035), and "interference of pain with mood" (P=.004).

CONCLUSION

Hopelessness, pain treatment, and "interference of pain with mood" may influence the quality of sleep in advanced stages of cancer.

摘要

目的

本研究的目的是评估晚期癌症患者的睡眠质量及其与疼痛、抑郁和绝望感的关系。

方法

研究对象为102名正在接受姑息治疗的晚期癌症患者。患者完成了一份睡眠质量量表，即匹兹堡睡眠质量指数（PSQI）；一份疼痛评估工具，即希腊简短疼痛量表；一份抑郁自评量表，即贝克抑郁量表；最后还有贝克绝望量表。

结果

多元回归分析（逐步法）显示，绝望感（P = 0.003）、“疼痛对情绪的干扰”（P < 0.0005）和强效阿片类药物（P = 0.010）似乎会影响患者的睡眠质量（PSOI）。在另一项回归分析（强制法）中，PSQI与阿片类药物（P = 0.013）、绝望感（P = 0.035）和“疼痛对情绪的干扰”（P = 0.004）显著相关。