Juergens Craig P, Lo Sidney, French John K, Leung Dominic Y C
Int J Cardiol. 2008 Jul 4;127(2):252-4. doi: 10.1016/j.ijcard.2007.02.059. Epub 2007 Apr 30.
We determined whether vaso-vagal syncope during sheath removal after percutaneous coronary intervention leads to a higher incidence of major adverse cardiac events including acute stent thrombosis, in 611 patients who participated in our previous trial assessing the impact of intravenous sedation and local anaesthesia at this time on patient comfort. A total of 35 (5.7%) patients experienced a vaso-vagal reaction. Major adverse cardiac events at day 30 occurred in 5.7% of patients experiencing vaso-vagal syncope and 7.1% of those who did not (p=1.00) with no case of stent thrombosis in the vaso-vagal group. Whilst unpleasant for patients, we conclude that vaso-vagal syncope during sheath removal after percutaneous coronary intervention is not associated with increased adverse cardiac events in the stent era.
在611名参与我们之前试验的患者中，我们确定了经皮冠状动脉介入治疗后拔除鞘管期间发生的血管迷走性晕厥是否会导致包括急性支架血栓形成在内的主要不良心脏事件发生率更高，该试验评估了此时静脉镇静和局部麻醉对患者舒适度的影响。共有35名（5.7%）患者发生血管迷走反应。血管迷走性晕厥患者中30天时主要不良心脏事件发生率为5.7%，未发生血管迷走反应的患者中为7.1%（p = 1.00），血管迷走组无支架血栓形成病例。虽然对患者来说不愉快，但我们得出结论，在支架时代，经皮冠状动脉介入治疗后拔除鞘管期间的血管迷走性晕厥与不良心脏事件增加无关。
