脂质双层膜的层间摩擦力和表面剪切粘度。
Intermonolayer friction and surface shear viscosity of lipid bilayer membranes.
作者信息
den Otter W K, Shkulipa S A
机构信息
Computational Biophysics, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
出版信息
Biophys J. 2007 Jul 15;93(2):423-33. doi: 10.1529/biophysj.107.105395. Epub 2007 Apr 27.
Abstract
The flow behavior of lipid bilayer membranes is characterized by a surface viscosity for in-plane shear deformations, and an intermonolayer friction coefficient for slip between the two leaflets of the bilayer. Both properties have been studied for a variety of coarse-grained double-tailed model lipids, using equilibrium and nonequilibrium molecular dynamics simulations. For lipids with two identical tails, the surface shear viscosity rises rapidly with tail length, while the intermonolayer friction coefficient is less sensitive to the tail length. Interdigitation of lipid tails across the bilayer midsurface, as observed for lipids with two distinct tails, strongly enhances the intermonolayer friction coefficient, but hardly affects the surface shear viscosity. The simulation results are compared against the available experimental data.
摘要
脂质双分子层膜的流动行为具有以下特征
平面内剪切变形的表面粘度，以及双层膜两个小叶之间滑动的层间摩擦系数。使用平衡和非平衡分子动力学模拟，对多种粗粒化双尾模型脂质的这两种特性进行了研究。对于具有两条相同尾巴的脂质，表面剪切粘度随尾巴长度迅速增加，而层间摩擦系数对尾巴长度不太敏感。如在具有两条不同尾巴的脂质中观察到的那样，脂质尾巴跨双层中间表面的交错排列强烈增强了层间摩擦系数，但几乎不影响表面剪切粘度。将模拟结果与现有的实验数据进行了比较。
相似文献
1
Intermonolayer friction and surface shear viscosity of lipid bilayer membranes.
Biophys J. 2007 Jul 15;93(2):423-33. doi: 10.1529/biophysj.107.105395. Epub 2007 Apr 27.
2
Surface viscosity, diffusion, and intermonolayer friction: simulating sheared amphiphilic bilayers.
Biophys J. 2005 Aug;89(2):823-9. doi: 10.1529/biophysj.105.062653. Epub 2005 May 13.
3
Hydrodynamic shear dissipation and transmission in lipid bilayers.
Proc Natl Acad Sci U S A. 2021 May 25;118(21). doi: 10.1073/pnas.2100156118.
4
Interleaflet sliding in lipidic bilayers under shear flow: comparison of the gel and fluid phases using reversed non-equilibrium molecular dynamics simulations.
Phys Chem Chem Phys. 2014 Feb 7;16(5):2154-66. doi: 10.1039/c3cp53238k.
5
Thermal undulations of lipid bilayers relax by intermonolayer friction at submicrometer length scales.
Phys Rev Lett. 2006 May 5;96(17):178302. doi: 10.1103/PhysRevLett.96.178302. Epub 2006 May 3.
6
Lipid membranes with transmembrane proteins in shear flow.
J Chem Phys. 2010 Jan 14;132(2):025101. doi: 10.1063/1.3285269.
7
Surface Shear Viscosity and Interleaflet Friction from Nonequilibrium Simulations of Lipid Bilayers.
J Chem Theory Comput. 2019 Nov 12;15(11):6471-6481. doi: 10.1021/acs.jctc.9b00683. Epub 2019 Sep 30.
8
Determining the local shear viscosity of a lipid bilayer system by reverse non-equilibrium molecular dynamics simulations.
Chemphyschem. 2009 Sep 14;10(13):2305-15. doi: 10.1002/cphc.200900156.
9
Comparison of ternary bilayer mixtures with asymmetric or symmetric unsaturated phosphatidylcholine lipids by coarse grained molecular dynamics simulations.
J Phys Chem B. 2012 Mar 22;116(11):3525-37. doi: 10.1021/jp212406u. Epub 2012 Mar 9.
10
Lipid bilayer perturbations around a transmembrane nanotube: a coarse grain molecular dynamics study.
Biophys J. 2005 Jun;88(6):3822-8. doi: 10.1529/biophysj.104.057703. Epub 2005 Mar 18.
引用本文的文献
1
Forces and Flows at Cell Surfaces.
J Membr Biol. 2023 Dec;256(4-6):331-340. doi: 10.1007/s00232-023-00293-x. Epub 2023 Sep 29.
2
Self-Assembly of Lipid Molecules under Shear Flows: A Dissipative Particle Dynamics Simulation Study.
Biomolecules. 2023 Sep 7;13(9):1359. doi: 10.3390/biom13091359.
3
Protein Crowding and Cholesterol Increase Cell Membrane Viscosity in a Temperature Dependent Manner.
J Chem Theory Comput. 2023 May 9;19(9):2630-2643. doi: 10.1021/acs.jctc.3c00060. Epub 2023 Apr 18.
4
Surface viscosities of lipid bilayers determined from equilibrium molecular dynamics simulations.
Biophys J. 2023 Mar 21;122(6):1094-1104. doi: 10.1016/j.bpj.2023.01.038. Epub 2023 Feb 4.
5
Sensing a little friction.
Biophys J. 2022 Aug 2;121(15):2827-2829. doi: 10.1016/j.bpj.2022.06.034. Epub 2022 Jun 30.
6
Systematic measurements of interleaflet friction in supported bilayers.
Biophys J. 2022 Aug 2;121(15):2981-2993. doi: 10.1016/j.bpj.2022.06.023. Epub 2022 Jun 25.
7
A vesicle microrheometer for high-throughput viscosity measurements of lipid and polymer membranes.
Biophys J. 2022 Mar 15;121(6):910-918. doi: 10.1016/j.bpj.2022.02.015. Epub 2022 Feb 15.
8
Assembly and Analysis of Cell-Scale Membrane Envelopes.
J Chem Inf Model. 2022 Feb 14;62(3):602-617. doi: 10.1021/acs.jcim.1c01050. Epub 2021 Dec 15.
9
Mechanical properties of anionic asymmetric bilayers from atomistic simulations.
J Chem Phys. 2021 Jun 14;154(22):224701. doi: 10.1063/5.0048232.
10
Scaling relationships for the elastic moduli and viscosity of mixed lipid membranes.
Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23365-23373. doi: 10.1073/pnas.2008789117. Epub 2020 Sep 3.
本文引用的文献
1
Diffusion of liquid domains in lipid bilayer membranes.
J Phys Chem B. 2007 Apr 5;111(13):3328-31. doi: 10.1021/jp0702088. Epub 2007 Mar 13.
2
Simulations of the dynamics of thermal undulations in lipid bilayers in the tensionless state and under stress.
J Chem Phys. 2006 Dec 21;125(23):234905. doi: 10.1063/1.2402919.
3
Dynamics in atomistic simulations of phospholipid membranes: Nuclear magnetic resonance relaxation rates and lateral diffusion.
J Chem Phys. 2006 Nov 28;125(20):204703. doi: 10.1063/1.2393240.
4
Dynamical motions of lipids and a finite size effect in simulations of bilayers.
J Chem Phys. 2006 Oct 14;125(14):144710. doi: 10.1063/1.2354486.
5
Size-dependent diffusion of membrane inclusions.
Biophys J. 2006 Oct 1;91(7):2393-8. doi: 10.1529/biophysj.106.087031. Epub 2006 Jul 7.
6
Thermal undulations of lipid bilayers relax by intermonolayer friction at submicrometer length scales.
Phys Rev Lett. 2006 May 5;96(17):178302. doi: 10.1103/PhysRevLett.96.178302. Epub 2006 May 3.
7
Area compressibility and buckling of amphiphilic bilayers in molecular dynamics simulations.
J Chem Phys. 2005 Dec 1;123(21):214906. doi: 10.1063/1.2132287.
8
Influence of chain length and unsaturation on sphingomyelin bilayers.
Biophys J. 2006 Feb 1;90(3):851-63. doi: 10.1529/biophysj.105.067371. Epub 2005 Nov 11.
9
Tunable generic model for fluid bilayer membranes.
Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Jul;72(1 Pt 1):011506. doi: 10.1103/PhysRevE.72.011506. Epub 2005 Jul 26.
10
Surface viscosity, diffusion, and intermonolayer friction: simulating sheared amphiphilic bilayers.
Biophys J. 2005 Aug;89(2):823-9. doi: 10.1529/biophysj.105.062653. Epub 2005 May 13.
Zotero 插件