Wahl J C, Katz H R, Abrams D A
Sinai Hospital of Baltimore, MD 21215.
Ann Ophthalmol. 1991 Jun;23(6):234-7.
One hundred thirty cases of ulcerative keratitis occurring from 1985 to 1989 at Sinai Hospital of Baltimore were reviewed. Positive corneal cultures were obtained from 40% of cases. The most common isolates were Staphylococcus epidermidis (28%), S. aureus (16%), and Pseudomonas aeruginosa. P. aeruginosa was the most common in contact lens wearers. Antibiotic pretreatment did not affect the rate of positive cultures significantly. Bilateral conjunctival and eyelid margin cultures also were examined. An association was found between corneal and ipsilateral conjunctival isolates (P = .05). Gram stains were consistently negative. Most patients were treated successfully as outpatients. The value of simultaneous conjunctival and eyelid margin cultures and Gram stains was questioned.
对1985年至1989年在巴尔的摩西奈医院发生的130例溃疡性角膜炎病例进行了回顾。40%的病例角膜培养呈阳性。最常见的分离菌是表皮葡萄球菌（28%）、金黄色葡萄球菌（16%）和铜绿假单胞菌。铜绿假单胞菌在隐形眼镜佩戴者中最为常见。抗生素预处理对阳性培养率没有显著影响。还检查了双侧结膜和睑缘培养物。发现角膜分离菌与同侧结膜分离菌之间存在关联（P = 0.05）。革兰氏染色一直为阴性。大多数患者作为门诊病人成功治愈。同时进行结膜和睑缘培养及革兰氏染色的价值受到质疑。
