Sanabria Alvaro, Carvalho André L, Silver Carl E, Rinaldo Alessandra, Shaha Ashok R, Kowalski Luiz P, Ferlito Alfio
Department of Surgery, Universidad de La Sabana, Bogotá, Colombia.
J Surg Oncol. 2007 Sep 1;96(3):273-80. doi: 10.1002/jso.20821.
Thyroidectomy is a common surgical procedure. The results of some clinical trials suggest that routine drainage does not offer advantages, but the evidence is not strong either in favor of or against this intervention. The effect of routine drainage compared to no drainage in patients subject to thyroidectomy was measured using a meta-analysis. After an extensive literature review, suitable randomized clinical trials were selected for analysis. Outcome measures included the comparative incidence of neck hematoma or seroma and length of hospital stay. Eleven randomized clinical trials were included. There were no statistically significant differences in the incidence of neck hematoma/seroma (OR 1.03, 95% CI 0.59-1.81) between the groups. The mean length of hospital stay was 1.53 days longer for the drainage group (95% CI 1.39-1.68). There was no difference found between routine drainage and no drainage with regard to the frequency of postoperative hematoma/seroma in patients following thyroidectomy. In addition, the mean length of hospital stay was longer in the routine drainage group.
甲状腺切除术是一种常见的外科手术。一些临床试验结果表明，常规引流并无优势，但支持或反对这种干预措施的证据都不充分。通过荟萃分析来衡量甲状腺切除患者常规引流与不引流相比的效果。在广泛查阅文献后，选择了合适的随机临床试验进行分析。结果指标包括颈部血肿或血清肿的比较发生率以及住院时间。纳入了11项随机临床试验。两组之间颈部血肿/血清肿的发生率无统计学显著差异（比值比1.03，95%置信区间0.59 - 1.81）。引流组的平均住院时间长1.53天（95%置信区间1.39 - 1.68）。甲状腺切除术后患者常规引流与不引流在术后血肿/血清肿的发生频率方面没有差异。此外，常规引流组的平均住院时间更长。
