一名婴儿对质子泵抑制剂产生严重的全身性不良反应。

Severe systemic adverse reaction to proton pump inhibitors in an infant.

作者信息

Baldassarre Emanuele, Sagaon Mario Mendoza, Ferrarini Alessandra, Bianchetti Mario G

机构信息

Division of Pediatric Surgery, Ospedale San Giovanni, Bellinzona, Switzerland.

出版信息

Pediatr Pulmonol. 2007 Jun;42(6):563-4. doi: 10.1002/ppul.20616.

DOI:10.1002/ppul.20616

PMID:17469150

Abstract

Episodes of respiratory distress with chest retraction and wheezing, sometimes associated with facial edema, were noted after administering the proton pump inhibitors omeprazole and esomeprazole in an infant with gastroesophageal reflux. The disturbances relieved dramatically after withdrawing the proton pump inhibitor.

摘要

在一名患有胃食管反流的婴儿中，给予质子泵抑制剂奥美拉唑和埃索美拉唑后，出现了伴有胸部回缩和喘息的呼吸窘迫发作，有时还伴有面部水肿。停用质子泵抑制剂后，这些症状显著缓解。