Vojniković Bozidar, Njirić Sanja, Zamolo Gordana, Toth Ivan, Apanjol Josip, Coklo Miran
Eye Polyclinic "Dr. B. Vojniković", Rijeka, Croatia.
Coll Antropol. 2007 Jan;31 Suppl 1:39-41.
In the 1975-2004 period, 130 cases of pterygium were estimated, 83 males and 47 females, on a small island Rab. Island Rab is located in the north part of the Adriatic sea, which has very high index of sun radiation. Pterygium is usually histopathologically defined as a hyperplasia of conjunctival tissue, elastoid degeneration of subepithelieum and fragmentation of Bowman's membrane. Our histopathological findings in 73 eyes are following: conjunctiva with neovascularisation, leukocyte margination and subepithelial basophilic degeneration, proliferation of conjunctival tissue, acanthosis and squamous metaplasia, and mucinous elements, focaly present plasma cells, focuses of increased pigmentisation in basal epithelial layers, tenon capsule with edema, diffuse neovascularisation and fragmentation of fibrils. These findings suggest that in severe cases of pterygium histopathologically exists precancerosis. In conclusion, on the basis of these histopathological findings, especially in the Tenon capsule, we suggest that for surgical procedure of pterygium the excision of the Tenon capsule, extensively under pterygium, is necessary.
在1975年至2004年期间，在拉布小岛上估计有130例翼状胬肉病例，其中男性83例，女性47例。拉布岛位于亚得里亚海北部，该地区太阳辐射指数非常高。翼状胬肉通常在组织病理学上被定义为结膜组织增生、上皮下弹性样变性和鲍曼膜破碎。我们对73只眼睛的组织病理学发现如下：结膜伴有新生血管形成、白细胞靠边和上皮下嗜碱性变性、结膜组织增生、棘层增厚和鳞状化生，以及黏液成分，局部出现浆细胞，基底上皮层色素沉着增加灶，眼球筋膜囊伴有水肿、弥漫性新生血管形成和纤维原纤维破碎。这些发现表明，在严重的翼状胬肉病例中，组织病理学上存在癌前病变。总之，基于这些组织病理学发现，尤其是在眼球筋膜囊，我们建议对于翼状胬肉的手术操作，有必要在翼状胬肉下方广泛切除眼球筋膜囊。
