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泊沙康唑成功治疗肾移植术后毛霉坏死性筋膜炎并挽救肢体

Successful treatment and limb salvage of mucor necrotizing fasciitis after kidney transplantation with posaconazole.

作者信息

Harada Abigail S, Lau William

机构信息

Department of Medicine, University of Hawai'i, John A. Burns School of Medicine, Honolulu, HI 96813, USA.

出版信息

Hawaii Med J. 2007 Mar;66(3):68-71.

PMID:17472045
Abstract

This is a case of mucormycosis complicated by necrotizing fasciitis in a renal transplant recipient on immunosuppressive therapy treated with posaconazole. Mucormycosis occurs most commonly as an opportunistic infection in the immunocompromised host. This patient, with predisposing risk factors for infection, including diabetes mellitus status post cadaveric renal transplantation on immunosuppressive therapy, is the first reported case of successful treatment of Mucor involving an extremity which was neither fatal nor required extremity amputation.

摘要

这是一例肾移植受者在接受免疫抑制治疗并使用泊沙康唑治疗过程中发生毛霉病合并坏死性筋膜炎的病例。毛霉病最常作为免疫功能低下宿主中的机会性感染出现。该患者具有感染的易感风险因素,包括糖尿病、尸体肾移植术后接受免疫抑制治疗,是首例成功治疗累及肢体的毛霉病且既未致命也未进行截肢的报道病例。

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Successful treatment and limb salvage of mucor necrotizing fasciitis after kidney transplantation with posaconazole.泊沙康唑成功治疗肾移植术后毛霉坏死性筋膜炎并挽救肢体
Hawaii Med J. 2007 Mar;66(3):68-71.
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引用本文的文献

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Mucormycosis infection following intravenous access in the forearm.前臂静脉穿刺后发生毛霉菌病感染。
Can J Plast Surg. 2010 Summer;18(2):e30-2.
2
[Infections in organ transplantations].[器官移植中的感染]
Pathologe. 2011 Mar;32(2):159-64. doi: 10.1007/s00292-010-1404-0.
3
Skin and soft tissue infections in the transplant population.移植人群中的皮肤和软组织感染。
Curr Infect Dis Rep. 2008 Sep;10(5):387-93. doi: 10.1007/s11908-008-0063-2.