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环状萎缩性扁平苔藓

Annular atrophic lichen planus.

作者信息

Ponce-Olivera Rosa María, Tirado-Sánchez Andrés, Montes-de-Oca-Sánchez Griselda, León-Dorantes Gladys, Mercadillo-Pérez Patricia

机构信息

Servicio de Dermatología and Servicio de Dermatopatología, Hospital General de México, Mexico City, Mexico.

出版信息

Int J Dermatol. 2007 May;46(5):490-1. doi: 10.1111/j.1365-4632.2007.02964.x.

Abstract

A 30-year-old woman presented with a 1-year history of a pruritic eruption on the extremities, characterized by several annular plaques. The patient had been treated unsuccessfully with medium-potency topical steroids. The lesions had an erythematous papular border with an atrophic center (width, 1-4 cm) (Fig. 1). No oral, genital, or nail lesions were observed. A skin biopsy from one of the plaques was performed. Histopathologic examination of the raised border showed hyperkeratosis of the stratum corneum, focal thickening of the granular layer, basal liquefaction degeneration of the epidermis, and a band-like subepidermal infiltration with numerous Civatte bodies. In the center of the lesion, the epidermis became thinner (Fig. 2). Elastic fibers were reduced or absent in the papillary dermis. The patient was treated with high-potency topical steroids for 2 months with clinical improvement.

摘要

一名30岁女性,四肢出现瘙痒性皮疹1年,表现为多个环状斑块。患者曾使用中效外用类固醇治疗但未成功。皮损有红斑丘疹边界,中央萎缩(宽度1 - 4厘米)(图1)。未观察到口腔、生殖器或指甲病变。对其中一个斑块进行了皮肤活检。隆起边界的组织病理学检查显示角质层角化过度、颗粒层局灶性增厚、表皮基底液化变性以及表皮下带状浸润伴大量Civatte小体。在皮损中央,表皮变薄(图2)。乳头真皮层弹性纤维减少或缺失。患者接受高效外用类固醇治疗2个月后临床症状改善。

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