Alinovi A, Barella P A, Benoldi D
Int J Dermatol. 1983 Jan-Feb;22(1):37-8. doi: 10.1111/j.1365-4362.1983.tb02111.x.
A 71-year-old white man was first seen in September 1978. He complained of an asymptomatic recurrent red patch, which had been slowly enlarging for two months on the glans penis. The patient stated he had a similar lesion a year before, which disappeared completely after one month of treatment with a topical corticosteroid. Physical examination revealed a single, glistening, erythematous, round patch, 1.5 cm in diameter, on the dorsal surface of the glans penis. The central area seemed somewhat depressed with minute erosions scattered over the lesion (Fig. 1). The inguinal nodes were not enlarged and nothing was found on the skin or other mucous membranes. The diagnoses entertained at that time were plasma cell balanitis, erythroplasia of Queyrat, fixed drug eruption, lichen planus, erosive balanitis and solitary plasmocytoma. Laboratory studies were normal. A biopsy of the lesion showed: ulcerated or atrophic epidermis; hypergranulosis; hydropic degeneration of the basal layer; many Civatte bodies within the lower epidermis and the upper zone of papillary dermis; occasional clefts between the epidermis and the dermis; a band-like infiltrate in the papillary dermis, which composed almost entirely of plasma cells, seemed to impinge on the epidermis (Fig. 2). The lesion was diagnosed as lichen planus, erosive type. The patch disappeared in about 4 weeks with topical steroids. No relapse has occurred after a year.
一名71岁白人男性于1978年9月首次就诊。他主诉阴茎头出现一个无症状的复发性红斑,已缓慢扩大两个月。患者称一年前有过类似病变,经外用皮质类固醇治疗一个月后完全消失。体格检查发现阴茎头背侧有一个直径1.5厘米的单一、发亮、红斑性圆形斑块。中心区域似乎有些凹陷,病变上散在微小糜烂(图1)。腹股沟淋巴结未肿大,皮肤或其他黏膜未发现异常。当时考虑的诊断有浆细胞性龟头炎、凯腊增殖性红斑、固定性药疹、扁平苔藓、糜烂性龟头炎和孤立性浆细胞瘤。实验室检查正常。病变活检显示:表皮溃疡或萎缩;颗粒层增厚;基底层水肿变性;表皮下部和乳头真皮上层有许多西瓦特小体;表皮与真皮间偶尔有裂隙;乳头真皮内有一条几乎完全由浆细胞组成的带状浸润,似乎侵犯表皮(图2)。病变诊断为糜烂型扁平苔藓。外用类固醇治疗约4周后斑块消失。一年后未复发。