Zhou Hai-Yan, Luo Dan, Pu Xiao-Lan
Department of Dermatology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Department of Dermatology, Peng'an County People's Hospital, Nanchong 637800, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 Mar;54(2):447-449. doi: 10.12182/20230360203.
A 36-year-old female patient came to our hospital with the chief complaint of having white patches on her waist for 10-plus years and having new annular plaques appearing on the white patches for 6-plus months. Wood's lamp examination done in the hospital showed a positive result. Histopathology of skin tissue from the edge of the annular swelling on the right waist revealed epidermal hyperkeratosis, wedge-shaped thickening of the granular layer, liquefactive degeneration of the basal cells, and a band-like infiltration of lymphocytes in the superficial dermis. The patient was diagnosed with vitiligo combined with annular lichen planus (ALP). The patient was treated with topical halometasone cream administered twice a day. The purplish-red annular plagues subsided and disappeared almost completely one month after the treatment was started and no signs of recurrence were observed duringn the 2-month follow-up. ALP is a rare variant of lichen planus. There has been no reported case of vitiligo combined with ALP so far.
一名36岁女性患者因腰部出现白色斑块10余年，白色斑块上出现新的环状斑块6个多月前来我院就诊。我院进行的伍德灯检查结果呈阳性。右腰环状肿胀边缘皮肤组织的组织病理学检查显示，表皮角化过度，颗粒层呈楔形增厚，基底细胞液化变性，真皮浅层有带状淋巴细胞浸润。该患者被诊断为白癜风合并环状扁平苔藓（ALP）。患者接受外用卤米松乳膏治疗，每日两次。治疗开始1个月后，紫红色环状斑块几乎完全消退消失，在2个月的随访期间未观察到复发迹象。ALP是扁平苔藓的一种罕见变体。迄今为止，尚无白癜风合并ALP的病例报道。
