Brinker Mark R, O'Connor Daniel P, Crouch C Craig, Mehlhoff Thomas L, Bennett James B
Center for Problem Fractures and Limb Restoration, Houston, TX 77030-4509, USA.
J Orthop Trauma. 2007 Mar;21(3):178-84. doi: 10.1097/BOT.0b013e318032c4d8.
To report the functional outcomes of Ilizarov treatment of infected nonunion of the distal humerus.
Prospective case series.
Tertiary referral center.
Between July 1998 and August 2003, 6 consecutive patients (age 33 to 73 years) were referred to us with an infected nonunion of the distal humerus following failure of open reduction and internal fixation. The average time from initial injury to presentation with the nonunion was 27 months (range, 6 to 99 months). The average number of prior surgeries was 2.8 (range, 1 to 4).
Hardware removal, ulnar nerve neurolysis, 1 stage debridement, autogenous bone grafting, and application of an Ilizarov external fixator with acute compression in the operating room followed by slow gradual compression (0.25-0.50 mm per day) for several weeks postoperatively.
Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire; SF-12 Physical Component Scale (PCS); Brief Pain Inventory; quality-adjusted life years.
All patients attained bony union. One patient refractured 3 weeks after removal of the external fixator following a fall and ultimately underwent total elbow arthroplasty. At an average follow-up of 4.1 years (range, 2 to 7 years), none of the remaining 5 patients had undergone any additional surgery on their arm and all were free of infection. For these 5 patients, significant improvements were seen in standardized DASH scores (42% initially to 78% at follow-up, P = 0.017), worst pain intensity ratings (5.4 initially to 0.8 at follow-up, P = 0.007), and SF-12 PCS scores (37 initially to 44 at follow-up, P = 0.041). On average, the pretreatment to posttreatment improvement was equivalent to 3.8 quality-adjusted life years.
Ilizarov treatment of infected distal humeral nonunions that have failed internal fixation restores function, decreases pain, and improves quality of life. The Ilizarov method should be considered a primary treatment option for this disabling and difficult clinical problem.
报告应用伊里扎洛夫技术治疗肱骨远端感染性骨不连的功能结果。
前瞻性病例系列研究。
三级转诊中心。
1998年7月至2003年8月期间,6例连续患者(年龄33至73岁)因切开复位内固定失败后出现肱骨远端感染性骨不连被转诊至我院。从初始损伤至出现骨不连的平均时间为27个月(范围6至99个月)。既往手术的平均次数为2.8次(范围1至4次)。
取出内固定物、尺神经松解、一期清创、自体骨移植,并在手术室应用伊里扎洛夫外固定器并进行急性加压,术后数周进行缓慢渐进性加压(每天0.25 - 0.50毫米)。
上肢、肩部和手部功能障碍(DASH)问卷;SF - 12身体成分量表(PCS);简明疼痛量表;质量调整生命年。
所有患者均实现骨愈合。1例患者在去除外固定器3周后因跌倒发生再骨折,最终接受了全肘关节置换术。在平均4.1年(范围2至7年)的随访中,其余5例患者均未对其上肢进行任何额外手术,且均无感染。对于这5例患者,标准化DASH评分有显著改善(初始为42%,随访时为78%,P = 0.017),最严重疼痛强度评分(初始为5.4,随访时为0.8,P = 0.007),以及SF - 12 PCS评分(初始为37,随访时为44,P = 0.041)。平均而言,治疗前至治疗后的改善相当于3.8个质量调整生命年。
伊里扎洛夫技术治疗切开复位内固定失败的肱骨远端感染性骨不连可恢复功能、减轻疼痛并改善生活质量。对于这一致残且棘手的临床问题,伊里扎洛夫方法应被视为主要治疗选择。