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使用泰勒空间框架修复胫骨骨不连和骨缺损。

Repair of tibial nonunions and bone defects with the Taylor Spatial Frame.

作者信息

Rozbruch S Robert, Pugsley Jacob S, Fragomen Austin T, Ilizarov Svetlana

机构信息

Institute for Limb Lengthening and Reconstruction Limb Lengthening and Deformity Service, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York, USA.

出版信息

J Orthop Trauma. 2008 Feb;22(2):88-95. doi: 10.1097/BOT.0b013e318162ab49.

Abstract

OBJECTIVE

To investigate the outcomes of tibial nonunions and bone defects treated with the Taylor Spatial Frame (TSF) using the Ilizarov method.

DESIGN

Retrospective.

SETTING

Limb Lengthening and Deformity Service at an academic medical center.

PATIENTS

Thirty-eight consecutive patients with 38 tibial nonunions were treated with the TSF. There were 23 patients with bone defects (average 5.9 cm) and 22 patients with leg-length discrepancy (LLD) (average 3.1 cm) resulting in an average longitudinal deficiency (sum of bone defect and LLD) of 6.5 cm in 31 patients (1-16). The average number of previous surgeries was 4 (0-20). At the time of surgery, 19 (50%) nonunions were diagnosed as infected.

INTERVENTION

All patients underwent repair of the nonunion and application of a TSF. Patients with bone loss were additionally treated with lengthening. Infected nonunions were treated with 6 weeks of culture-specific antibiotics.

MAIN OUTCOME MEASUREMENTS

Bony union, time in frame, eradication of infection, leg-length discrepancy, deformity, Short Form-36 (SF-36) scores, American Academy of Orthopaedic Surgeons (AAOS) lower-limb scores, and Association for the Study of the Method of Ilizarov (ASAMI) bone and functional results.

RESULTS

Bony union was achieved after the initial treatment in 27 (71%) patients. The presence of bone infection correlated with initial failure and persistent nonunion (P=0.03). The 11 persistent nonunions were re-treated with TSF reapplication in 4, intramedullary rodding in 3, plate fixation in 2, and amputation in 2 patients. This resulted in final bony union in 36 (95%) patients. The average LLD was 1.8 cm (0-6.8) (SD 2). Alignment with deformity less than 5 degrees was achieved in 32 patients and alignment between 6 degrees and 10 degrees was achieved in 4 patients. Significant improvement of Short Form-36 (SF-36) scores was noted in physical role (P=0.03) and physical function (P=0.001). AAOS lower-limb module scores significantly improved from 56 to 82 (P<0.001). ASAMI bone and functional outcomes were excellent or good in 36 and 34 patients, respectively. The number of previous surgeries correlated inversely with the ASAMI bone (P=0.003) and functional (P=0.001) scores.

CONCLUSIONS

One can comprehensively approach tibial nonunions with the TSF. This is particularly useful in the setting of stiff hypertrophic nonunion, infection, bone loss, LLD, and poor soft-tissue envelope. Infected nonunions have a higher risk of failure than noninfected cases. Treatment after fewer failed surgeries will lead to a better outcome. Internal fixation can be used to salvage initial failures.

摘要

目的

采用伊利扎洛夫方法,使用泰勒空间框架(TSF)研究胫骨骨不连和骨缺损的治疗结果。

设计

回顾性研究。

地点

一家学术医疗中心的肢体延长与畸形治疗科室。

患者

连续38例胫骨骨不连患者接受了TSF治疗。其中23例存在骨缺损(平均5.9厘米),22例存在腿长差异(LLD)(平均3.1厘米),导致31例患者(1 - 16)平均纵向缺损(骨缺损与LLD之和)为6.5厘米。既往手术平均次数为4次(0 - 20次)。手术时,19例(50%)骨不连被诊断为感染。

干预措施

所有患者均接受骨不连修复及TSF应用。骨缺损患者还接受了延长治疗。感染性骨不连患者接受了为期6周的针对性抗生素治疗。

主要观察指标

骨愈合、框架佩戴时间、感染根除情况、腿长差异、畸形、简明健康状况调查量表(SF - 36)评分、美国矫形外科医师学会(AAOS)下肢评分以及伊利扎洛夫方法研究协会(ASAMI)骨与功能结果。

结果

27例(71%)患者在初始治疗后实现了骨愈合。骨感染的存在与初始治疗失败及持续性骨不连相关(P = 0.03)。11例持续性骨不连患者中,4例再次应用TSF治疗,3例采用髓内棒固定,2例采用钢板固定,2例截肢。最终36例(95%)患者实现了骨愈合。平均LLD为1.8厘米(0 - 6.8)(标准差2)。32例患者畸形矫正小于5度,4例患者畸形矫正介于6度至10度之间。简明健康状况调查量表(SF - 36)评分在生理功能(P = 0.03)和身体功能(P = 0.001)方面有显著改善。AAOS下肢模块评分从56分显著提高至82分(P < 0.001)。ASAMI骨与功能结果分别在36例和34例患者中为优或良。既往手术次数与ASAMI骨(P = 0.003)和功能(P = 0.001)评分呈负相关。

结论

使用TSF可全面治疗胫骨骨不连。这在僵硬性肥大性骨不连、感染、骨缺损、LLD及软组织条件差的情况下尤其有用。感染性骨不连比非感染性病例失败风险更高。较少失败手术次数后的治疗将带来更好的结果。可采用内固定挽救初始治疗失败的情况。

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