Lyszczarz Robert, Stypułkowska Jadwiga, Stepniewski Marek, Szot Wojciech M
Zakładu Chirurgii Stomatologicznej Instytutu Stomatologii, Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
Wiad Lek. 2002;55 Suppl 1(Pt 2):768-72.
At a basis of many pathologic reactions lie disturbances in balance between production of free radicals and antioxidant organism capability. In our study we evaluate antioxidant capability of saliva, as a Ferric Reducing Ability of Plasma (FRAP). 74 pupils selected from active swimmer class (age 11.48 +/- 0.48) were included into our study. Children examination consisted of evaluation of oral cavity Approximated Plate Index (API), tooth decay index (PUW) and %PUW (PUW as a fraction of all evaluated teeth). The average FRAP was 0.55 +/- 0.11 mmol/l. Value of 0.44 was selected as a lower normal limit. 20% of children (group I) were below that value, while the rest 80% (group II) achieved values above this limit. Both groups had API Index values below 25%, which comply as an optimum hygiene of oral cavity. We also observed greater PUW values in group I when compared to group II (4.2 vs 2.8 respectively), and greater %PUW (16.69 vs. 12.75). Decreased values of FRAP indicated convergence with worse status of oral cavity. Significant novelty of our study is correlation between oral cavity status and FRAP, which until now was only used for determination of antioxidant capability of blood plasma.
许多病理反应的基础是自由基产生与机体抗氧化能力之间的平衡失调。在我们的研究中，我们评估了唾液的抗氧化能力，即血浆铁还原能力（FRAP）。从活跃游泳班挑选的74名学生（年龄11.48±0.48岁）纳入我们的研究。儿童检查包括评估口腔简化菌斑指数（API）、龋齿指数（PUW）和%PUW（PUW占所有评估牙齿的比例）。平均FRAP为0.55±0.11 mmol/l。选择0.44作为下限正常值。20%的儿童（第一组）低于该值，而其余80%（第二组）的值高于此限。两组的API指数值均低于25%，符合口腔最佳卫生标准。与第二组相比，我们还观察到第一组的PUW值更高（分别为4.2和2.8），以及更高的%PUW（16.69对12.75）。FRAP值降低表明与口腔状况变差有关。我们研究的显著新颖之处在于口腔状况与FRAP之间的相关性，而FRAP迄今为止仅用于测定血浆的抗氧化能力。
