[Participation of peptide hydra morphogen in the regulation of proliferation processes in different tissues of white rats].
作者信息
Khomichuk A Iu, Timoshin S S
出版信息
Biull Eksp Biol Med. 1991 Sep;112(9):307-9.
PMID:1747486
Abstract
The PMH influence on proliferation processes in some tissues of white rats was studied. PMH injections in doses 10.0 mkg/kg and 100.0 mkg/kg stimulated the processes of DNA--synthesis after 24 hours in corneal and tongue epithelium. The direct dose-dependent effect was revealed. PMH in dose 10.0 mkg/kg activated the proliferative processes in the stomach epithelium and thymus cortex. after 24 hours too. The given dose of PMH caused trustworthy decreasing of proliferative activity in thymus after 4 hours. The stimulation of DNA-synthesis and acceleration of mitosis were found after 5-times application on white rat's corneal with 100 nM PMH solution.
摘要
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