Kirwan John R, Minnock Patricia, Adebajo Ade, Bresnihan Barry, Choy Ernest, de Wit Maarten, Hazes Mieke, Richards Pam, Saag Kenneth, Suarez-Almazor Maria, Wells George, Hewlett Sarah
University of Bristol Academic Rheumatology Unit, and United Bristol Healthcare NHS Trust, Bristol, UK.
J Rheumatol. 2007 May;34(5):1174-7.
The Patient Perspective Workshop at OMERACT 8 considered evidence for the importance of fatigue to patients with rheumatoid arthritis (RA) and whether measurement of fatigue meets the requirements of the OMERACT filter. The workshop participants included 20 patients from 10 countries and 60 other OMERACT participants. Introductory papers and detailed notes for discussion group members set out the evidence from the literature and from recent analyses of clinical study data available to several participants. The workshop concluded that fatigue is a symptom that is important to patients, is commonly reported by patients, is often severe, can be measured by several current instruments that pass the OMERACT filter, is responsive to some interventions, and provides information additional to that commonly obtained from currently used outcomes. The final OMERACT plenary session endorsed by a very large majority (89%) the proposal that, in addition to the "core set" of outcome measures currently in widespread use, fatigue should be measured in future studies of RA whenever possible.
在国际风湿病学临床研究规范制定组织（OMERACT）第8届会议上举办的患者视角研讨会，探讨了疲劳对类风湿关节炎（RA）患者的重要性的证据，以及疲劳测量是否符合OMERACT筛选标准。研讨会参与者包括来自10个国家的20名患者和60名其他OMERACT参会者。为讨论组成员准备的介绍性论文和详细笔记列出了文献及部分参会者可获取的临床研究数据近期分析中的证据。研讨会得出结论，疲劳是一种对患者很重要的症状，患者普遍会报告该症状，且常常较为严重，目前有几种通过OMERACT筛选标准的工具可对其进行测量，疲劳对某些干预措施有反应，并且能提供一些当前常用结局指标之外的信息。在OMERACT的最后全体会议上，绝大多数人（89%）支持一项提议，即除了目前广泛使用的“核心”结局指标集外，在未来的RA研究中应尽可能对疲劳进行测量。
