Kirwan John R, Hewlett Sarah
University of Bristol Academic Rheumatology Unit, United Bristol Healthcare NHS Trust, and Faculty of Health and Social Care, University of the West of England, Bristol, UK.
J Rheumatol. 2007 May;34(5):1171-3.
The experience of fatigue has been reported by a large proportion of people with rheumatoid arthritis (RA), and it is often the most important problem for individual patients. A systematic analysis of patient focus group discussions revealed 3 overarching themes: fatigue is overwhelming and different from normal tiredness; it permeates every sphere of life; and self-management is variable, but professional support is rare. A systematic search for articles measuring fatigue discovered 23 scales, 6 of which have sufficient evidence of validity to pass the OMERACT filter. Some preliminary data indicate that fatigue measurement is sensitive to change induced by some interventions in RA. This issue, and the question of whether measuring fatigue adds additional information to measurements made using the current core set of measures, will be addressed at OMERACT 8.
很大一部分类风湿关节炎（RA）患者都有疲劳的体验，而且这通常是个体患者最重要的问题。对患者焦点小组讨论的系统分析揭示了3个总体主题：疲劳难以承受且不同于正常的疲倦；它渗透到生活的各个领域；自我管理因人而异，但专业支持很少。对测量疲劳的文章进行系统检索发现了23种量表，其中6种有足够的效度证据通过OMERACT筛选标准。一些初步数据表明，疲劳测量对RA中某些干预措施引起的变化敏感。这个问题，以及测量疲劳是否会为使用当前核心指标集所做的测量增加额外信息的问题，将在OMERACT 8会议上讨论。
