Stein Paul D, Beemath Afzal, Quinn Deborah A, Olson Ronald E, Goodman Lawrence R, Gottschalk Alexander, Hales Charles A, Hull Russell D, Leeper Kenneth V, Sostman H Dirk, Weg John G, Woodard Pamela K
Department of Research, St. Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA.
Am J Cardiol. 2007 May 1;99(9):1303-5. doi: 10.1016/j.amjcard.2006.12.051. Epub 2007 Mar 16.
Data from the Prospective Investigation of Pulmonary Embolism Diagnosis II (PIOPED II) were evaluated to test the hypothesis that the performance of multidetector computed tomographic (CT) pulmonary angiography and CT venography is independent of a patient's age and gender. In 773 patients with adequate CT pulmonary angiography and 737 patients with adequate CT pulmonary angiography and CT venography, the sensitivity and specificity for pulmonary embolism for groups of patients aged 18 to 59, 60 to 79, and 80 to 99 years did not differ to a statistically significant extent, nor were there significant differences according to gender. Overall, however, the specificity of CT pulmonary angiography was somewhat greater in women, but in men and women, it was > or =93%. In conclusion, the results indicate that multidetector CT pulmonary angiography and CT pulmonary angiography and CT venography may be used with various diagnostic strategies in adults of all ages and both genders.
对肺栓塞诊断前瞻性调查II（PIOPED II）的数据进行了评估，以检验以下假设：多排螺旋计算机断层扫描（CT）肺动脉造影和CT静脉造影的表现与患者的年龄和性别无关。在773例CT肺动脉造影充分的患者以及737例CT肺动脉造影和CT静脉造影充分的患者中，年龄在18至59岁、60至79岁以及80至99岁的患者组对肺栓塞的敏感性和特异性在统计学上无显著差异，按性别分类也无显著差异。然而，总体而言，CT肺动脉造影的特异性在女性中略高，但在男性和女性中均≥93%。总之，结果表明多排螺旋CT肺动脉造影以及CT肺动脉造影和CT静脉造影可用于所有年龄和性别的成年人的各种诊断策略。
