Scudamore C H, Chow Y, Shackleton C R, Forward A D
Department of Surgery, University of British Columbia, Vancouver.
Can J Surg. 1991 Dec;34(6):543-6.
The frequency of pancreatic carcinoma appears to be increasing. Effective treatment is essential for most patients whose tumours are unresectable. Definitive treatment by stenting techniques are currently limited to those patients who are high surgical risks, elderly, present with metastatic disease or refuse the surgical option. Surgical bypass offers the best palliation and should reliably decompress the biliary obstruction caused by the tumour with the least surgical trauma. Roux-en-Y choledochojejunostomy (CDJ), with or without a gastroenterostomy, is usually the preferred method of bypass; however, for patients with a distended gallbladder this procedure is often made easier by its removal. Even then providing a proximal, tension-free anastomosis can be challenging. In 13 consecutive patients who still had a gallbladder and required a biliary bypass for carcinoma of the pancreas, the authors interposed the gallbladder between the proximal bile ducts and a Roux-en-Y loop. This procedure could be done more quickly than CDJ and performed well.
胰腺癌的发病率似乎在上升。对于大多数肿瘤无法切除的患者来说,有效的治疗至关重要。目前,支架置入技术的确定性治疗仅限于那些手术风险高、年龄较大、患有转移性疾病或拒绝手术选择的患者。手术旁路提供了最佳的姑息治疗,应以最小的手术创伤可靠地解除肿瘤引起的胆道梗阻。无论是否进行胃肠吻合术,Roux-en-Y胆总管空肠吻合术(CDJ)通常是首选的旁路手术方法;然而,对于胆囊扩张的患者,切除胆囊通常会使该手术更容易进行。即便如此,实现近端无张力吻合仍具有挑战性。在13例仍有胆囊且因胰腺癌需要进行胆道旁路手术的连续患者中,作者将胆囊置于近端胆管和Roux-en-Y肠袢之间。该手术比CDJ完成得更快,且效果良好。