van Oosterhout Joep J G, Laufer Miriam K, Perez M Arantza, Graham Stephen M, Chimbiya Nelson, Thesing Phillip C, Alvarez-Martinez Miriam J, Wilson Paul E, Chagomerana Maganizo, Zijlstra Eduard E, Taylor Terrie E, Plowe Christopher V, Meshnick Steven R
University of Malawi College of Medicine, Blantyre, Malawi.
Emerg Infect Dis. 2007 Feb;13(2):325-8. doi: 10.3201/eid1302.060462.
In a prospective study of 660 HIV-positive Malawian adults, we diagnosed Pneumocystis jirovecii pneumonia (PcP) using clinical features, induced sputum for immunofluorescent staining, real-time PCR, and posttreatment follow-up. PcP incidence was highest in patients with the lowest CD4 counts, but PcP is uncommon compared with incidences of pulmonary tuberculosis and bacterial pneumonia.
在一项针对660名马拉维成年HIV阳性患者的前瞻性研究中,我们通过临床特征、诱导痰免疫荧光染色、实时聚合酶链反应以及治疗后随访来诊断耶氏肺孢子菌肺炎(PcP)。PcP发病率在CD4计数最低的患者中最高,但与肺结核和细菌性肺炎的发病率相比,PcP并不常见。