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[人类传染性软疣与多形红斑]

[Human orf and erythema multiforme].

作者信息

Mourtada I, Le Tourneur M, Chevrant-Breton J, Le Gall F

机构信息

Service de Dermatologie, CHU Pontchaillou, rue Henri-Le Guilloux, 35033 Rennes, France.

出版信息

Ann Dermatol Venereol. 2000 Apr;127(4):397-9.

Abstract

BACKGROUND

Orf is a disease of sheep due to a parapoxvirus. Transmission in man is possible, and is generally benign, self-limited condition. Although, rare complications have been mentioned. We report a case of Orf with erythema multiforme in a young girl.

CASE REPORT

A 13-year-old girl presented to our department with an erythema multiform. The cutaneous examination revealed painless erythematous nodule of her right index finger developed 15 days after a contact with a lamb. The diagnosis of Orf complicated by erythema multiforme was made on the basis of her typical history. Lesions heal with symptomatic therapy in 15 days.

DISCUSSION

Orf presents in sheeps as a pustular dermatitis or a vesicular oral mucosal lesions, and in man as a single lesion on the site of infection. This lesion generally heals without complications, although secondary infection is not uncommon. Twenty one cases of erythema multiforme have been recorded following infection with the Orf virus. In typical cases, the diagnosis is established by a history of contact with infected animals and the appearance of the lesion. Electron microscopic examination can be helpful sometimes. Lesions regress in 4 to 5 weeks without specific treatment.

摘要

背景

羊痘是由副痘病毒引起的绵羊疾病。人类有可能感染,通常为良性、自限性疾病。不过,也有罕见并发症的报道。我们报告一例年轻女孩患羊痘并伴有多形红斑的病例。

病例报告

一名13岁女孩因多形红斑前来我科就诊。皮肤检查发现,她在与一只羔羊接触15天后,右手食指出现无痛性红斑结节。根据其典型病史,诊断为羊痘并发多形红斑。经对症治疗,皮损在15天内愈合。

讨论

羊痘在绵羊身上表现为脓疱性皮炎或口腔黏膜水疱性病变,在人类身上则表现为感染部位的单个病变。这种病变通常无并发症而愈合,不过继发感染并不少见。已有21例在感染羊痘病毒后出现多形红斑的记录。在典型病例中,根据与感染动物接触史及病变表现即可确诊。电子显微镜检查有时可能会有帮助。未经特殊治疗,皮损在4至5周内消退。

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