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牙科急诊患者椅旁C反应蛋白的快速定量测定

Rapid quantitative determination of C-reactive protein at chair side in dental emergency patients.

作者信息

Ren Yan-Fang, Malmstrom Hans S

机构信息

University of Rochester, Eastman Dental Center, Rochester, NY 14620, USA.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jul;104(1):49-55. doi: 10.1016/j.tripleo.2007.01.007. Epub 2007 May 7.

DOI:10.1016/j.tripleo.2007.01.007
PMID:17482849
Abstract

OBJECTIVES

The objective of this study was to quantitatively determine, at chair side, the serum C-reactive protein (CRP) levels in dental emergency patients.

STUDY DESIGN

Quantitative CRP test was performed at chair side in 40 patients with acute alveolar abscess (AAA), acute periodontal abscess (APA), and alveolar osteitis (AO) at the time of dental emergency treatment and 1 week after. CRP levels were compared between groups and before and after treatments using ANOVA and Fisher's Exact tests.

RESULTS

Serum CRP levels were greater than 5 mg/L in 30 (75%) of the 40 patients. At 1-week follow-up, the decline in CRP levels was evident in the AAA group (P < .05), but not statistically significant in the APA and AO groups (P > .05).

CONCLUSION

Serum CRP levels are often elevated in patients with odontogenic infections and postoperative complications. Rapid reduction in serum CRP levels was likely to occur following successful treatment of AAA, but less likely to occur in APA and AO.

摘要

目的

本研究的目的是在椅旁定量测定牙科急诊患者的血清C反应蛋白(CRP)水平。

研究设计

对40例急性牙槽脓肿(AAA)、急性牙周脓肿(APA)和干槽症(AO)患者在牙科急诊治疗时及治疗1周后在椅旁进行CRP定量检测。采用方差分析和Fisher精确检验比较各组之间以及治疗前后的CRP水平。

结果

40例患者中有30例(75%)血清CRP水平大于5mg/L。在1周随访时,AAA组CRP水平明显下降(P<.05),但APA组和AO组无统计学意义(P>.05)。

结论

牙源性感染和术后并发症患者血清CRP水平常升高。AAA成功治疗后血清CRP水平可能迅速下降,但APA和AO则不太可能。

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